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Bleonix15mg/vial

Injection
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Beacon Pharmaceuticals Ltd.
Generic: Bleomycin
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Bleonix. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Bleonix is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in s... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Bleonix is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
DrivingDriving
UNSAFE
Bleonix may cause side effects which could affect your ability to drive. As with $med_name, few people have reported that they feel tired or weak after ... View More
KidneyKidney
CAUTION
Bleonix should be used with caution in patients with kidney disease. Dose adjustment of Bleonix may be needed. Please consult your doctor.
LiverLiver
SAFE IF PRESCRIBED
Bleonix is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Bleonix may not be needed in the... View More
descriptionMedical Overview

Introduction

Bleonix is a medicine used for treatment of cancer in various parts of the body such as cervical, Cancer of the mouth, nasopharynx and paranasal sinuses... View More

Uses of Bleonix

  • Cervical cancer
  • Cancer of mouth, nasopharynx and paranasal sinuses, larynx, oesophagus
  • Skin cancer

Side effects of Bleonix

Common
  • Fever
  • Hair loss
  • Interstitial pneumonia
  • Loss of appetite
  • Low blood platelets
  • Nail discoloration
  • Nausea
  • Pulmonary fibrosis
  • Rigors
  • Scratch dermatitis
  • Skin pigmentation
  • Stomatitis (Inflammation of the mouth)
  • Vomiting
  • Weight loss

How to use Bleonix

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Bleonix works

Bleonix is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

quick tipsQuick Tips
  • Inform your doctor before taking bleomycin if you have severe heart disease, kidney problems, lung problems requiring use of oxygen, impaired liver func... View More
  • Inform your doctor before taking bleomycin if you are taking other anticancer/cytotoxic drugs such as vinca alkaloids or cisplatin, drugs such as clozap... View More
  • Seek immediate medical advice if you develop dry cough, breathlessness, rapid breathing or any other lung problems.
  • Do not drive or operate heavy machinery after taking this drug as it may make you feel weak or tired.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.
descriptionBrief Description

Indication

Lymphoma, Squamous cell or Testicular tumours, Malignant effusions

Administration

IV/IM Preparation IV: reconstitute 15 U vial in 5 mL & 30 U vial in 10 mL NS to yield 3 U/mL solution IM/SC: reconstitute 15 U vial in 1-5 mL & 30 U... View More

Adult Dose

Squamous Cell Carcinoma, Testicular Carcinoma 0.25-0.5 unit/kg (10 to 20 unit/m²) IV/IM/SC q1-2Weeks Hodgkin's Disease, Non-Hodgkin's Lymphoma Admi... View More

Child Dose

Not recommended

Renal Dose

Renal Impairment CrCl >50 mL/min: Dose adjustment not necessary CrCl 40-50 mL/min: 70% of normal dose CrCl 30-40 mL/min: 60% of normal dose Cr... View More

Contraindication

Hypersensitivity. Severe pulmonary disease; pregnancy and lactation.

Mode of Action

Bleomycin causes breakage of single- and double- stranded DNA by binding to DNA and inhibiting DNA synthesis. To a lesser extent, it also inhibits RNA a... View More

Precaution

Pulmonary infection, preexisting pulmonary function impairment, renal impairment. Patients who received radiotherapy, particularly to the thorax. Regula... View More

Side Effect

>10% Mucocutaneous toxicity including rash, erythema, hyperpigmentation, urticaria (>50%),Febrile reactions, acute (25-50%),Mucositis (30%),Stomatitis ... View More

Pregnancy Category Note

Pregnancy Category: D Lactation: It is not known whether the drug is excreted in milk. Because of the potential for serious adverse reactions in nurs... View More

Interaction

Increased incidence and severity of lung toxicity w/ previous or concurrent radiotherapy to the chest. Combination w/ vinca alkaloids may result to a sy... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More