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Tacrol0.03%

Ointment
rx_reqRequire Prescription
The ACME Laboratories Ltd.
Generic: Tacrolimus 0.1%, 0.03% Topical
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descriptionSafety Advices
AlcoholAlcohol
No interaction found/established
PregnancyPregnancy
CONSULT YOUR DOCTOR
Tacrol may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing ... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Tacrol is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
DrivingDriving
No interaction found/established
KidneyKidney
No interaction found/established
LiverLiver
No interaction found/established
descriptionMedical Overview

Introduction

Tacrol is used to treat eczema (atopic dermatitis). It works by suppressing the activity of certain immune cells that cause inflammation (redness and sw... View More

Uses of Tacrol

Side effects of Tacrol

Common
  • Application site reactions (burning, irritation, itching and redness)

How to use Tacrol

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and ... View More

How Tacrol works

Tacrol is an immunosuppressant. It works by suppressing the activity of certain immune cells that cause inflammation (redness and swelling) of the skin.... View More

What if you forget to take Tacrol?

If you miss a dose of Tacrol, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your re... View More

quick tipsQuick Tips
  • Tacrol is effective at treating eczema (atopic dermatitis) when other treatment options have failed.
  • It works by decreasing itching, redness, and skin rashes.
  • Apply thinly, to affected areas of skin only. Clean the affected area and dry well before applying Tacrol. Avoid contact with water after application.
  • Inform your doctor if there's no improvement even after two weeks of treatment, or if the skin gets worse.
  • Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
  • Stop using Tacrol and consult your doctor if your eczema becomes infected.
  • Continuous long-term use of the ointment should be avoided. Use as prescribed by you doctor.
descriptionBrief Description

Indication

Atopic dermatitis, Allergic contact dermatitis, Severe eczema, Psoriasis, Alopecia areata, Pyoderma gangrenosum, Cutaneous lupus erythematosus, Dermatom... View More

Administration

Apply a thin layer of Tacrolim ointment onto the affected skin areas and rub in gently and completely. Treatment should be continued for one week after ... View More

Adult Dose

Topical/Cutaneous Atopic dermatitis Adult: Apply thinly 0.03% or 0.1% ointment to affected area bid. Rub in gently and completely. For short-term and ... View More

Child Dose

Topical/Cutaneous Atopic dermatitis <2 years old: Not recommended Child: 2-15 yr: Apply thinly 0.03% oint to affected area bid. Rub in gently and c... View More

Contraindication

Tacrolimus ointment is contraindicated in patients with a history of hypersensitivity to Tacrolimus or any other component of the preparation.

Mode of Action

Tacrolimus inhibits T-lymphocyte activation, although the exact mechanism of action unclear. Tacrolimus bind to cytosolic receptors known as immunophili... View More

Precaution

Monitoring of blood trough serum concentrations to prevent organ rejection and to reduce drug-related toxicity. Topical: Used with caution on the face o... View More

Side Effect

>10% Burning sensation (43-58%), Pruritus (41-46%), Flu-like symptoms (23-31%), Skin erythema (12-28%), Headache (5-20%)

Interaction

Increased nephrotoxicity with ciclosporin, aminoglycosides, amphotericin B, cisplatin, NSAIDs, vancomycin, co-trimoxazole, aciclovir, ganciclovir. Incre... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More