Carboplat450mg/45ml
Injection
Beacon Pharmaceuticals Ltd.
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| Alcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Carboplat. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Carboplat is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in... View More |
| Breastfeeding | UNSAFE Carboplat is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. |
| Driving | UNSAFE Carboplat may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. |
| Kidney | CAUTION Carboplat should be used with caution in patients with kidney disease. Dose adjustment of Carboplat may be needed. Please consult your doctor.
Use of Ca... View More |
| Liver | SAFE IF PRESCRIBED Carboplat is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Carboplat may not be needed in... View More |
Introduction
Carboplat is used in the treatment of ovarian cancer and small cell lung cancer. It shows its working by stopping or slowing down the growth of cancer c... View More
Uses of Carboplat
- Ovarian cancer
- Small cell lung cancer
Side effects of Carboplat
- Nausea
- Vomiting
- Anemia (low number of red blood cells)
- Fatigue
- Low blood platelets
- Increased liver enzymes
- Decreased white blood cell count (neutrophils)
- Stomatitis (Inflammation of the mouth)
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Diarrhea
How to use Carboplat
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Carboplat works
Carboplat is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multipl... View More
What if you forget to take Carboplat?
If you miss a dose of Carboplat, please consult your doctor.
- It is given as an injection into the veins under the supervision of a doctor.
Indication
Ovarian carcinoma, Lung cancer
Administration
IV Preparation Single-dose lyophilized powder (reconstitution require) Reconstitute powder with sterile water for injection, D5W, or 0.9% NaCl to yiel... View More
Adult Dose
Intravenous Small cell lung cancer; Advanced ovarian carcinoma Adult: IV As single agent in treatment-naive patients: 400 mg/m2; As single agent in ... View More
Child Dose
Solid tumor 300-600 mg/m² IV q4Weeks Sarcoma (bone/soft tissue) 400 mg/m²/day for 2 days every 21 days Brain tumor 175 mg/m² qWeek x 4 weeks w... View More
Renal Dose
Renal impairment: CrCl (ml/min) >40 Recommended dose: 400 mg/m2. 20-39 Recommended dose: 250 mg/m2.
Contraindication
Previous allergy; pregnancy, lactation; allergy to other platinum compounds; severe bone marrow depression; significant bleeding, aluminium containing n... View More
Mode of Action
Carboplatin is an alkylating agent which binds covalently to DNA. It modifies the cell cycle by interfering with DNA structure and function.
Precaution
Neonates; diminished renal function; neurotoxicity; liver function impairment. Lactation: not known if excreted in breast milk; do not nurse
Side Effect
>10% Leukopenia (26-97%),Neutropenia (21-96%),Nausea (81-93%),Vomiting (81-93%),Anemia (14-90%),Magnesium loss (43-61%),Thrombocytopenia (33-66%),Alope... View More
Pregnancy Category Note
Pregnancy Category: D Lactation: not known if excreted in breast milk; do not nurse
Interaction
Increased risk of ototoxicity when used with aminoglycosides.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More