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Square Pharmaceuticals PLC.
Generic: Fondaparinux
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descriptionSafety Advices
It is unsafe to consume alcohol with Fonidel.
Fonidel is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there... View More
Fonidel is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
It is not known whether Fonidel alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and rea... View More
Fonidel should be used with caution in patients with kidney disease. Dose adjustment of Fonidel may be needed. Please consult your doctor. Use of Fonide... View More
Fonidel should be used with caution in patients with severe liver disease. Dose adjustment of Fonidel may be needed. Please consult your doctor.
descriptionMedical Overview


Fonidel is an anticoagulant medicine used in the treatment of deep vein thrombosis (clot in veins of leg) and pulmonary embolism (clot in artery of lung... View More

Uses of Fonidel

  • Deep vein thrombosis
  • Pulmonary embolism

Side effects of Fonidel

  • Bleeding
  • Anemia (low number of red blood cells)

How to use Fonidel

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Fonidel works

Fonidel is an anticoagulant. It stops the action of a substance (clotting factor Xa) from working in the blood. This prevents the formation of unwanted ... View More

What if you forget to take Fonidel?

If you miss a dose of Fonidel, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your r... View More

quick tipsQuick Tips
  • Fonidel prevents the formation of blood clots in the blood vessels of legs or lungs.
  • It may make you feel dizzy, tired or weak. Do not drive or do anything that requires mental focus until you know how it affects you.
  • It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
  • Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
  • Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.
descriptionBrief Description


Venous thromboembolic events, acute DVT, pulmonary embolism (PE), unstable angina, non-ST segment elevation MI


Administration Administer initial dose 6-8 hours after surgery, once hemostasis has been established SC administration is deep, alternating right an... View More

Adult Dose

Deep Vein Thrombosis/Acute Pulmonary Embolism Treatment <50 kg: 5 mg SC once daily 50-100 kg: 7.5 mg SC once daily >100 kg: 10 mg SC once daily Adm... View More

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment: CrCl (ml/min) Dosage Recommendation <20 Contraindicated. 20-50 1.5 mg once daily.


Hypersensitivity. Active clinically significant bleeding, acute bacterial endocarditis.

Mode of Action

Fondaparinux, a synthetic pentasaccharide, acts as a selective inhibitor of activated factor X. It works by binding selectively to ATIII, and potentiate... View More


Patient w/ increased risk of haemorrhage (e.g. congenital or acquired bleeding disorders, history or active GI ulceration, intracranial haemorrhage, rec... View More

Side Effect

>10% Anemia (1-20%),Fever (4-14%),Nausea (3-11%) 1-10% Rash (7.5%),Dizziness (4%),Confusion (3%),Constipation (5-9%),Diarrhea (2-3%),Edema (9%),Hea... View More

Pregnancy Category Note

Pregnancy Available data from published literature and postmarketing reports have not reported clear association with adverse developmental outcomes; f... View More


Increased risk of bleeding w/ (e.g. desirudin, fibrinolytic drugs, glycoprotein IIb/IIIa-receptor antagonists, heparin, heparinoids or LMWH).


The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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