Fonidel2.5mg/0.5ml
Injection
Square Pharmaceuticals PLC.
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| Alcohol | UNSAFE It is unsafe to consume alcohol with Fonidel. |
| Pregnancy | SAFE IF PRESCRIBED Fonidel is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there... View More |
| Breastfeeding | SAFE IF PRESCRIBED Fonidel is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. |
| Driving | CONSULT YOUR DOCTOR It is not known whether Fonidel alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and rea... View More |
| Kidney | CAUTION Fonidel should be used with caution in patients with kidney disease. Dose adjustment of Fonidel may be needed. Please consult your doctor.
Use of Fonide... View More |
| Liver | CAUTION Fonidel should be used with caution in patients with severe liver disease. Dose adjustment of Fonidel may be needed. Please consult your doctor. |
Introduction
Fonidel is an anticoagulant medicine used in the treatment of deep vein thrombosis (clot in veins of leg) and pulmonary embolism (clot in artery of lung... View More
Uses of Fonidel
- Deep vein thrombosis
- Pulmonary embolism
Side effects of Fonidel
- Bleeding
- Anemia (low number of red blood cells)
How to use Fonidel
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Fonidel works
Fonidel is an anticoagulant. It stops the action of a substance (clotting factor Xa) from working in the blood. This prevents the formation of unwanted ... View More
What if you forget to take Fonidel?
If you miss a dose of Fonidel, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your r... View More
- Fonidel prevents the formation of blood clots in the blood vessels of legs or lungs.
- It may make you feel dizzy, tired or weak. Do not drive or do anything that requires mental focus until you know how it affects you.
- It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
- Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
- Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.
Indication
Venous thromboembolic events, acute DVT, pulmonary embolism (PE), unstable angina, non-ST segment elevation MI
Administration
Administration Administer initial dose 6-8 hours after surgery, once hemostasis has been established SC administration is deep, alternating right an... View More
Adult Dose
Deep Vein Thrombosis/Acute Pulmonary Embolism Treatment <50 kg: 5 mg SC once daily 50-100 kg: 7.5 mg SC once daily >100 kg: 10 mg SC once daily Adm... View More
Child Dose
Safety and efficacy not established
Renal Dose
Renal impairment: CrCl (ml/min) Dosage Recommendation <20 Contraindicated. 20-50 1.5 mg once daily.
Contraindication
Hypersensitivity. Active clinically significant bleeding, acute bacterial endocarditis.
Mode of Action
Fondaparinux, a synthetic pentasaccharide, acts as a selective inhibitor of activated factor X. It works by binding selectively to ATIII, and potentiate... View More
Precaution
Patient w/ increased risk of haemorrhage (e.g. congenital or acquired bleeding disorders, history or active GI ulceration, intracranial haemorrhage, rec... View More
Side Effect
>10% Anemia (1-20%),Fever (4-14%),Nausea (3-11%) 1-10% Rash (7.5%),Dizziness (4%),Confusion (3%),Constipation (5-9%),Diarrhea (2-3%),Edema (9%),Hea... View More
Pregnancy Category Note
Pregnancy Available data from published literature and postmarketing reports have not reported clear association with adverse developmental outcomes; f... View More
Interaction
Increased risk of bleeding w/ (e.g. desirudin, fibrinolytic drugs, glycoprotein IIb/IIIa-receptor antagonists, heparin, heparinoids or LMWH).
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More