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Fungidal
Square Pharmaceuticals PLC.
Generic: Miconazole Nitrate 2% Topical
Medicine Overview of Fungidal 2% Cream
বাংলা
English
Indication
Skin and nail infections due to dermatophytes, yeasts and other fungi such as:, Tinea capitis, corporis, manuum, pedis, barbae, cruris, unguium or onychomycosis, Pityriasis versicolor, candidiasis of skin and nails, stomatitis angularis, otitis externa, mycoses secondarily infected with bacteria.
Adult Dose
Topical/Cutaneous
Adult:
Tinea cruris, corporis & cutaneous canidiasis: Apply to affected area BID for 2 weeks
Tinea versicolor: Apply once daily to affected area for 2 weeks
Tinea pedis: Apply BID to affected area for 4 weeks
Child Dose
Tinea
2 years: Apply BID for up to 1 month
Contraindication
History of sensitivity reactions to Miconazole or any of the components of the preparation.
Mode of Action
Miconazole inhibits ergosterol synthesis thus damaging fungal cell wall membrane and increases its permeability, allowing leakage of nutrients.
Precaution
For external use only. Avoid introduction into the eyes.
Lactation: not known whether distributed into milk; use caution
Side Effect
Irritation,BurningmMaceration,Allergic contact dermatitis
Irritation, burning, maceration, allergic contact dermatitis (all rare)
Interaction
May increase anticoagulant effect of warfarin. May increase or prolong the effect of the following drugs: Oral hypoglycaemics (e.g. sulfonylureas), phenytoin, HIV protease inhibitors (e.g. saquinavir), antineoplastic agents (e.g. vinca alkaloids, busulfan, docetaxel), Ca channel blockers (e.g. dihydropyridines, verapamil), immunosuppressive agents (e.g. ciclosporin, tacrolimus, sirolimus), carbamazepine, cilostazol, buspirone, disopyramide, alfentanil, sildenafil, alprazolam, brotizolam, midazolam IV, rifabutin, methylprednisolone, trimetrexate, ebastine and reboxetine. Potentially Fatal: Increased risk of cardiac arrhythmia w/ astemizole, cisapride, dofetilide, halofantrine, mizolastine, pimozide, quinidine, sertindole, terfenadine. May increase exposure to ergot alkaloids leading to ergotism. May increase the risk of rhabdomyolysis w/ HMG-CoA reductase inhibitors (e.g. simvastatin and...
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