Introduction
Nictoris 10 is a medicine used to prevent and treat heart-related chest pain (angina). It is usually prescribed when other heart medicines are not suitable or have not worked. It reduces the risk of an angina attack by widening blood vessels and improving blood flow to the heart.
Nictoris 10 may be taken with or without food. It should be swallowed whole with water at the same time(s) each day. Your doctor will decide the dose and how often you should take it. This may change from time to time depending on how well it is working. You should take this medicine regularly to get the maximum benefit, even if you feel fine. Doing so will help you prevent any further harm. If you stop taking it, your chest pain may come back. You can improve the health of your heart by making some lifestyle changes such as quitting smoking, cutting down on alcohol, eating well, exercising regularly and managing stress.
The most common side effect of this medicine is headache, especially during the first few days of treatment. You can reduce this by drinking plenty of fluids and avoiding alcohol, but it usually goes after a week. Other common side effects include feeling dizzy or weak, nausea and flushing (sense of warmth in the face, ears, neck and trunk). Talk to your doctor if these bother you or do not go away.
It is not suitable for some people. Tell your doctor if you have low blood pressure or heart failure. Also let your doctor know all other medications you are using as some may affect, or be affected by this medicine. You should not take any medicines for erectile dysfunction with this medicine. This medicine is not usually recommended during pregnancy or breastfeeding. Avoid drinking alcohol, as it can increase the blood pressure-lowering effect of this medicine. Your doctor may ask you to avoid salt substitutes.
Uses of Nictoris 10
- Angina (heart-related chest pain)
Side effects of Nictoris 10
Common
- Headache
- Nausea
- Vomiting
- Weakness
- Dizziness
- Flushing (sense of warmth in the face, ears, neck and trunk)
How to use Nictoris 10
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nictoris 10 may be taken with or without food, but it is better to take it at a fixed time.
How Nictoris 10 works
Nictoris 10 is a vasodilator. It works by reducing the workload of the heart. As a result, heart muscle does not need as much blood and oxygen supply. This reduces the frequency and severity of angina attacks.
What if you forget to take Nictoris 10?
If you miss a dose of Nictoris 10, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Indication
Angina pectoris
Administration
May be taken with or without food.
Adult Dose
Oral
Angina pectoris
Adult: 10 mg bid, increase if necessary. Usual dose: 10-20 mg bid. May use 5 mg bid for patients prone to headache. Max dose: 30 mg bid.
Hepatic impairment: Dose reduction may be necessary.
Contraindication
Cardiogenic shock; hypotension; left ventricular failure with low filling pressure; lactation.
Mode of Action
Nicorandil dilates arterioles and large coronary arteries by opening the potassium channels, and stimulates guanylate cyclase causing venous vasodilatation. It therefore reduces preload and afterload, and improves coronary blood flow.
Precaution
Hypovolaemia, low systolic BP, acute pulmonary oedema, pregnancy. May impair ability to drive or operate machinery.
Side Effect
Headache (usually transitory), flushing, dizziness, nausea, vomiting and weakness. Hypotension and reflex tachycardia at high doses.
Interaction
Hypotensive interaction may occur with alcohol, TCAs, antihypertensives and other vasodilators.
Potentially Fatal: Enhanced hypotensive effect with sildenafil and other phosphodiesterase type-5 inhibitors.