Xpos 100 DR100mg
Tablet
Square Pharmaceuticals Ltd.
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| Alcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Xpos 100 DR. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Xpos 100 DR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the develo... View More |
| Breastfeeding | CONSULT YOUR DOCTOR Xpos 100 DR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. |
| Driving | UNSAFE Xpos 100 DR may cause side effects which could affect your ability to drive.
As you may feel dizzy, sleepy, or have blurred vision while taking Xpos 100... View More |
| Kidney | CAUTION Xpos 100 DR should be used with caution in patients with kidney disease. Dose adjustment of Xpos 100 DR may be needed. Please consult your doctor.
Regul... View More |
| Liver | SAFE IF PRESCRIBED Xpos 100 DR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Xpos 100 DR may not be neede... View More |
Introduction
Xpos 100 DR belongs to a group of medicines called antifungals. It works by stopping the growth of fungus and is used to treat fungal infection. It kill... View More
Uses of Xpos 100 DR
- Severe fungal infections
Side effects of Xpos 100 DR
- Headache
- Vomiting
- Cough
- Nausea
How to use Xpos 100 DR
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Xpos 100 DR works
Xpos 100 DR is an antifungal medication. It kills fungi by destroying the fungal cell membrane. This treats your infection.
- Your doctor has prescribed Xpos 100 DR to cure your infection and improve symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- It is given as an injection under the supervision of a healthcare professional.
- Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin... View More
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Indication
Prophylaxis of invasive Aspergillus, Candida Infections, Oropharyngeal candidiasis
Administration
IV Preparation Equilibrate the refrigerated vial to room temperature Aseptically transfer 16.7 mL (300 mg) of solution to an IV bag/bottle containing ... View More
Adult Dose
Oral Prophylaxis of invasive fungal infections Adult: As delayed-release tab: 300 mg bid on the 1st day, then 300 mg once daily thereafter. As oral su... View More
Child Dose
Invasive Aspergillus & Candida Infections Indicated for prophylaxis of invasive Aspergillus and Candida infections in patients who are at high risk of ... View More
Renal Dose
Moderate-to-severe renal impairment (IV) eGFR <50 mL/min: Avoid IV administration unless benefit/risk assessment justifies use Accumulation of the IV ... View More
Contraindication
Hypersensitivity. Co-admin w/ sirolimus, ergot alkaloids (e.g. ergotamine, dihydroergotamine), CYP3A4 substrates (terfenadine, astemizole, cisapride, pi... View More
Mode of Action
Blocks the synthesis of ergosterol, a key component of the fungal cell membrane, through the inhibition of the enzyme lanosterol 14-α-demethylase and ac... View More
Precaution
Patient w/ potentially proarrhythmic conditions. Hepatic impairment. Pregnancy and lactation. Patient Counselling May impair ability to drive or operate... View More
Side Effect
>10% Fever (45%) Diarrhea (42%) Nausea (38%) Hypokalemia (30%) Headache (28%) Abd pain (27%) Anemia (25%) Cough (24%) Nausea (3... View More
Pregnancy Category Note
Pregnancy Available data in pregnant women are insufficient to establish a drug- associated risk of major birth defects, miscarriage, or adverse matern... View More
Interaction
Decreased plasma concentrations w/ efavirenz, fosamprenavir, cimetidine, esomeprazole, metoclopramide, phenytoin and rifabutin. May increase plasma conc... View More
Alternative brand for Xpos 100 DR
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More