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Xpos 100 DR100mg

Tablet
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Square Pharmaceuticals Ltd.
Generic: Posaconazole
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1800.00
MRP
2000.00
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Xpos 100 DR. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Xpos 100 DR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the develo... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Xpos 100 DR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
DrivingDriving
UNSAFE
Xpos 100 DR may cause side effects which could affect your ability to drive. As you may feel dizzy, sleepy, or have blurred vision while taking Xpos 100... View More
KidneyKidney
CAUTION
Xpos 100 DR should be used with caution in patients with kidney disease. Dose adjustment of Xpos 100 DR may be needed. Please consult your doctor. Regul... View More
LiverLiver
SAFE IF PRESCRIBED
Xpos 100 DR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Xpos 100 DR may not be neede... View More
descriptionMedical Overview

Introduction

Xpos 100 DR belongs to a group of medicines called antifungals. It works by stopping the growth of fungus and is used to treat fungal infection. It kill... View More

Uses of Xpos 100 DR

  • Severe fungal infections

Side effects of Xpos 100 DR

Common
  • Headache
  • Vomiting
  • Cough
  • Nausea

How to use Xpos 100 DR

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Xpos 100 DR works

Xpos 100 DR is an antifungal medication. It kills fungi by destroying the fungal cell membrane. This treats your infection.

quick tipsQuick Tips
  • Your doctor has prescribed Xpos 100 DR to cure your infection and improve symptoms.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • It is given as an injection under the supervision of a healthcare professional.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin... View More
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
descriptionBrief Description

Indication

Prophylaxis of invasive Aspergillus, Candida Infections, Oropharyngeal candidiasis

Administration

IV Preparation Equilibrate the refrigerated vial to room temperature Aseptically transfer 16.7 mL (300 mg) of solution to an IV bag/bottle containing ... View More

Adult Dose

Oral Prophylaxis of invasive fungal infections Adult: As delayed-release tab: 300 mg bid on the 1st day, then 300 mg once daily thereafter. As oral su... View More

Child Dose

Invasive Aspergillus & Candida Infections Indicated for prophylaxis of invasive Aspergillus and Candida infections in patients who are at high risk of ... View More

Renal Dose

Moderate-to-severe renal impairment (IV) eGFR <50 mL/min: Avoid IV administration unless benefit/risk assessment justifies use Accumulation of the IV ... View More

Contraindication

Hypersensitivity. Co-admin w/ sirolimus, ergot alkaloids (e.g. ergotamine, dihydroergotamine), CYP3A4 substrates (terfenadine, astemizole, cisapride, pi... View More

Mode of Action

Blocks the synthesis of ergosterol, a key component of the fungal cell membrane, through the inhibition of the enzyme lanosterol 14-α-demethylase and ac... View More

Precaution

Patient w/ potentially proarrhythmic conditions. Hepatic impairment. Pregnancy and lactation. Patient Counselling May impair ability to drive or operate... View More

Side Effect

>10% Fever (45%) Diarrhea (42%) Nausea (38%) Hypokalemia (30%) Headache (28%) Abd pain (27%) Anemia (25%) Cough (24%) Nausea (3... View More

Pregnancy Category Note

Pregnancy Available data in pregnant women are insufficient to establish a drug- associated risk of major birth defects, miscarriage, or adverse matern... View More

Interaction

Decreased plasma concentrations w/ efavirenz, fosamprenavir, cimetidine, esomeprazole, metoclopramide, phenytoin and rifabutin. May increase plasma conc... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More