Beximco Pharmaceuticals Ltd.
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Caution is advised when consuming alcohol with Apixa 5. Please consult your doctor.
Apixa 5 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there... View More
Apixa 5 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Apixa 5 does not usually affect your ability to drive.
Apixa 5 should be used with caution in patients with kidney disease. Dose adjustment of Apixa 5 may be needed. Please consult your doctor.
Apixa 5 should be used with caution in patients with liver disease. Dose adjustment of Apixa 5 may be needed. Please consult your doctor. Dose adjustmen... View More
Apixa 5 is a medicine known as an anticoagulant or blood thinner. It helps prevent and treat blood clots. It is used to reduce the risk of stroke and he... View More
Uses of Apixa 5
- Deep vein thrombosis
- Pulmonary embolism
- Stroke prevention
How to use Apixa 5
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Apixa 5 may be taken with ... View More
How Apixa 5 works
Apixa 5 is a novel oral anticoagulant (NOAC). It works by preventing the formation of blood clots in the body.
What if you forget to take Apixa 5?
If you miss a dose of Apixa 5, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your r... View More
- For best results, take Apixa 5 at the same time every day. It is better to take at night with meals
- It interacts less with food or other medicines. Hence, frequent dose changes are not required.
- It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. f... View More
- Inform your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
- If you are going to have a surgery or dental treatment, you may be asked to stop taking Apixa 5 temporarily.
- Notify your doctor if you have any kidney problem.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
- Do not stop taking medication without talking to your doctor.
Indicated to reduce risk of stroke and systemic embolism associated with nonvalvular atrial fibrillation, Postoperative Prophylaxis of DVT/PE following ... View More
May be taken with or without food.
Oral Adult Prevention of VTE: Elective hip or knee replacement surgery Tablet 2.5 mg twice daily. Initial dose should be taken 12-24 hr post-op. Re... View More
Renal impairment, including with ESRD on dialysis Deep Vein Thrombosis: No dose adjustment recommended; clinical efficacy and safety studies did not en... View More
Hypersensitivity. Clinically significant active bleeding. Hepatic disease associated w/ coagulopathy & clinically relevant bleeding risk. Lesion or cond... View More
Mode of Action
Apixaban is an anticoagulant that inhibits platelet activation and fibrin clot formation via direct, selective and reversible inhibition of free and clo... View More
Increased risk of hemorrhage eg, congenital or acquired bleeding disorders; active ulcerative GI disease; bacterial endocarditis; thrombocytopenia; plat... View More
Epistaxis, haematoma, anaemia, haematuria, contusion, nausea; GI, rectal or gingival haemorrhage. Potentially Fatal: Epidural or spinal haematoma, fata... View More
Pregnancy Category Note
Pregnancy There are no adequate and well-controlled studies in pregnant women Treatment is likely to increase the risk of hemorrhage during pregnanc... View More
Increased exposure w/ strong dual CYP3A4 and P-glycoprotein (P-gp) inhibitors (e.g. clarithromycin, itraconazole, ketoconazole, ritonavir). Increased ri... View More
Alternative brand for Apixa 5
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More