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Soforal-LP90mg+400mg

Tablet
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Beacon Pharmaceuticals Ltd.
Generic: Ledipasvir + Sofosbuvir
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Soforal-LP. Please consult your doctor.
PregnancyPregnancy
SAFE IF PRESCRIBED
Soforal-LP is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, th... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Soforal-LP is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
DrivingDriving
UNSAFE
Soforal-LP may cause side effects which could affect your ability to drive. Soforal-LP, when taken together with other medicines for the treatment of he... View More
KidneyKidney
CAUTION
Soforal-LP should be used with caution in patients with severe kidney disease. Dose adjustment of Soforal-LP may be needed. Please consult your doctor. ... View More
LiverLiver
SAFE IF PRESCRIBED
Soforal-LP is safe to use in patients with liver disease. No dose adjustment of Soforal-LP is recommended.
descriptionMedical Overview

Introduction

Soforal-LP is a combination of two antiviral medicines. This prescription medicine is used in the treatment of chronic hepatitis C virus (HCV) infection... View More

Uses of Soforal-LP

  • Chronic hepatitis C virus (HCV) infection

Side effects of Soforal-LP

Common
  • Tiredness
  • Headache

How to use Soforal-LP

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Soforal-LP may be taken wi... View More

How Soforal-LP works

Soforal-LP is a combination of two antiviral medicines: Ledipasvir and Sofosbuvir. They work by lowering the amount of hepatitis C virus in the body and... View More

quick tipsQuick Tips
  • Soforal-LP is used for the treatment of chronic hepatitis C virus (HCV) infection.
  • Take it with food, preferably at the same time everyday.
  • You will usually need to take this medicine every day for either 12 or 24 weeks.
  • Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time.
  • It may cause fatigue, dizziness, and blurred vision. Don't drive or do anything requiring concentration until you know how it affects you.
  • Soforal-LP may cause headaches. Drink plenty of water and take a suitable painkiller. Inform your doctor if it does not go away.
  • Your doctor may monitor your liver function and the amount of hepatitis C virus in your body regularly.
  • Do not stop taking this medicine without your doctor’s advice.
descriptionBrief Description

Indication

Chronic hepatitis C (CHC), genotype 1, 4 & 6 infection in adults.

Administration

Can be taken with or without food.

Adult Dose

Oral Hepatitis C Indicated for adults with chronic hepatitis C virus (HCV) genotypes 1, 4, 5, or 6 infection Recommended dosage: One tablet (90 mg of... View More

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment Mild or moderate: No dosage adjustment required Severe (eGFR <30 mL/min/1.73 m²) or ESRD: No dosage recommendation can be given

Contraindication

Hypersensitivity.

Mode of Action

Ledipasvir is an HCV NS5A inhibitor and Sofosbuvir is a nucleotide analog inhibitor of HCV NS5B polymerase. Ledipasvir is a potent inhibitor of HCV N... View More

Precaution

Bradycardia with Amiodarone coadministration: Serious symptomatic bradycardia may occur in patients taking Amiodarone, particularly in patients also rec... View More

Side Effect

>10% Asthenia (31-36%),Fatigue (4-18%),Headache (13-29%),Cough (5-11%) 1-10% Nausea (6-9%),Diarrhea (3-7%),Dizziness (1-5%),Dyspnea (3-9%),Insomnia... View More

Interaction

Reduced therapeutic effect w/ drugs that are potent P-gp inducers in the intestine (eg rifampicin, St. John's wort, carbamazepine & phenytoin), modafini... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More