Introduction
Catopil belongs to a group of medicines known as angiotensin converting enzyme (ACE) inhibitors. It is widely used to treat high blood pressure and hear... View More
Uses of Catopil
Side effects of Catopil
How to use Catopil
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Catopil may be taken with ... View More
How Catopil works
Catopil is an angiotensin converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessel so that blood flows more... View More
What if you forget to take Catopil?
If you miss a dose of Catopil, skip it and continue with your normal schedule. Do not double the dose.
Indication
Hypertension, Congestive heart failure, Post Myocardial infarction, Diabetic nephropathy
Administration
Should be taken on an empty stomach. Take on an empty stomach 1 hr before or 2 hr after meals.
Adult Dose
Adult: PO HTN Initial: 12.5 mg twice daily. Maintenance: 25-50 mg twice daily. Max: 50 mg 3 times/day. Elderly: Initially, 6.25 mg bid. Heart failu... View More
Child Dose
Oral Hypertension Child: Neonates and infants: 0.15 mg/kg. Max: 6 mg/kg in 2 or 3 divided doses according to response. Childn and adolescents: 0.3 mg/... View More
Renal Dose
Renal impairment: CrCl (ml/min) <10 Initially, 6.25 mg/day. Max: 37.5 mg/day. 10-20 Initially, 12.5 mg/day. Max: 75 mg/day. 21-40 Initially, 25 mg/... View More
Contraindication
Known hypersensitivity to the drug. Bilateral renal artery stenosis, hereditary angioedema; renal impairment; pregnancy.
Mode of Action
Captopril competitively inhibits the conversion of angiotensin I (ATI) to angiotensin II (ATII), thus resulting in reduced ATII levels and aldosterone s... View More
Precaution
Patients on diuretics or with sodium depletion should discontinue diuretics or increase sodium intake prior to initiation of therapy. Renal impairment, ... View More
Side Effect
>10% Hyperkalemia (1-11%) 1-10% Hypersensitivity rxns (4-7%),Skin rash (4-7%),Dysgeusia (2-4%),Hypotension (1-2.5%),Pruritus (2%),Cough (0.5-2%),Ch... View More
Pregnancy Category Note
Pregnancy Category: C; D in 2nd & 3rd trimesters Discontinue as soon as pregnancy detected; during the second and third trimesters of pregnancy, drug... View More
Interaction
Concurrent treatment w/ NSAIDs reduces hypotensive action and increases the risk of nephrotoxicity. Additive hyperkalaemic effect w/ K supplements, K-sp... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More