Introduction
Cavazide 300/12.5 is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated it... View More
Uses of Cavazide 300/12.5
Side effects of Cavazide 300/12.5
How to use Cavazide 300/12.5
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cavazide 300/12.5 may be t... View More
How Cavazide 300/12.5 works
Cavazide 300/12.5 is a combination of two medicines: Irbesartan and hydrochlorothiazide which lower blood pressure effectively. Irbesartan is an angiote... View More
Indication
Diabetic nephropathy, Hypertension
Adult Dose
Hypertension 150 mg/12.5 mg PO qDay intially; if needed, after 1-2 weeks may titrate up to 300 mg/25 mg PO qDay
Contraindication
Hypersensitivity; pregnancy and lactation.
Mode of Action
Hydrochlorothiazide inhibits the reabsorption of Na and chloride in the distal tubules causing increased excretion of Na and water K and hydrogen ions. ... View More
Precaution
Child <6 yr. Unilateral or bilateral renal artery stenosis; vol or Na depletion; aortic or mitral valve stenosis, hypertrophic cardiomyopathy. Lactat... View More
Side Effect
>10% Irbesartan Hyperkalemia (19%) 1-10% Chest pain (2%),Tachycardia (1%),Abnormal urination (2%),Musculoskeletal pain (6%),Flu-like syndrome (3%)... View More
Pregnancy Category Note
Pregnancy Category: C (1st trimester); D (2nd & 3rd trimesters)
Interaction
Other antihypertensives, lithium, K-sparing diuretics, K supplements, salt substitutes containing K. CNS depressants, antidiabetics, cholestyramine & co... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More