Balovir 4040mg

Indication

Influenza

Administration

Initiate treatment within 48 hr of influenza symptom onset Take orally as a single dose May be taken with or without food

Adult Dose

Hepatic impairment Moderate (Child-Pugh B) to normal: No clinically meaningful pharmacokinetic differences were observed Severe: Not studied

Child Dose

Influenza Indicated for treatment of acute uncomplicated influenza in patients who have been symptomatic for ?48 hr <12 years: Safety and efficacy n... View More

Renal Dose

Renal impairment CrCl >50 mL/min: Pharmacokinetic analysis did not identify a clinically meaningful effect Severe: Not studied

Contraindication

Hypersensitivity

Mode of Action

Inhibits cap-dependent endonuclease; it is thought to inhibit viral replication activity of the viral polymerase Inhibition accomplished by a method ... View More

Precaution

There is no evidence of efficacy in any illness caused by pathogens other than influenza viruses; serious bacterial infections may begin with influenzal... View More

Side Effect

1-10% Frequency of adverse effects listed below are less than or equal to those reported with placebo Diarrhea (3%) Bronchitis (2%) Nausea (1%... View More

Pregnancy Category Note

Pregnancy Data are not available Animal studies No adverse developmental effects observed in rats or rabbits with PO administration at exposures ap... View More

Interaction

Polyvalent cations Baloxavir (active metabolite) may form a chelate with polyvalent cations, such as calcium, aluminum, or magnesium, in food or medica... View More