Cefot 1g IV/IM is an antibiotic medicine used to treat bacterial infections in your body. It is effective in infections of the brain, lungs, ear, urinar... View More
Uses of Cefot 1g IV/IM
Side effects of Cefot 1g IV/IM
How to use Cefot 1g IV/IM
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Cefot 1g IV/IM works
Cefot 1g IV/IM is an antibiotic. It kills the bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for... View More
What if you forget to take Cefot 1g IV/IM?
If you miss a dose of Cefot 1g IV/IM, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to... View More
Pneumonia, Meningitis, Peritonitis, Pelvic inflammatory disease, Endometritis, Pelvic cellulitis, Gonorrhea, Skin and skin structure infections, Respira... View More
IV Preparation Intermittent injection: Reconstitute 1 or 2 g with 10 mL SWI Infusion: Reconstitute infusion bottles with 50 or 100 mL NS or D5W IM:... View More
Adult: Infections Caused by Susceptible Organisms Uncomplicated: 1 g IV or IM q12hr Moderate to severe: 1-2 g IV or IM q8hr More serious (bloodstre... View More
Children: IV, IM 50–180 mg/kg/day q6–8h 200–225 mg/kg/day for meningitis q6h Neonates: The recommended dosage is 50 mg/kg/day in 2 to 4 divided dos... View More
Renal impairment: Severe: After an initial loading dose of 1 g, half the daily dose w/o changing the frequency.
Hypersensitivity to cephalosporins.
Mode of Action
Cefotaxime binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in b... View More
History of penicillin allergy; colitis; impaired renal function; pregnancy, lactation. Lactation: Drug enters breast milk; use with caution
Colitis, Elevated blood urea nitrogen (BUN) and creatinine, Elevated hepatic transaminases, Fever. Pain at inj site; hypersensitivity reactions, rash, ... View More
Pregnancy Category Note
Pregnancy category: B Lactation: Drug enters breast milk; use with caution
Probenecid decreases cefotaxime elimination. Potentially Fatal: Nephrotoxicity with furosemide and aminoglycosides.