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PTU 5050gm

Tablet
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Renata Limited
Generic: Propylthiouracil
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with PTU 50. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
PTU 50 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in so... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
PTU 50 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not har... View More
DrivingDriving
CONSULT YOUR DOCTOR
It is not known whether PTU 50 alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and reac... View More
KidneyKidney
SAFE IF PRESCRIBED
PTU 50 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of PTU 50 may not be needed in thes... View More
LiverLiver
CONSULT YOUR DOCTOR
There is limited information available on the use of PTU 50 in patients with liver disease. Please consult your doctor.
descriptionMedical Overview

Introduction

PTU 50 belongs to a group of medicine called anti-thyroid agents. It is used in the treatment of hyperthyroidism. It works by reducing the production of... View More

Uses of PTU 50

  • Hyperthyroidism

Side effects of PTU 50

Common
  • Skin rash
  • Hair loss
  • Headache
  • Pain
  • Joint stiffness
  • Nausea
  • Skin pigmentation
  • Paresthesia (tingling or pricking sensation)

How to use PTU 50

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. PTU 50 may be taken with o... View More

How PTU 50 works

PTU 50 is an anti-thyroid medication. It works by reducing the amount of thyroid hormones produced by the thyroid gland.

quick tipsQuick Tips
  • PTU Tablet is used for the treatment of hyperthyroidism.
  • You may have to stop taking it for a while if you are also taking radio-iodine as a treatment for your overactive thyroid.
  • It may affect the level of blood cells in your blood. Inform your doctor if you experience symptoms such as unexplained bruising or bleeding, sore throa... View More
  • Stop taking PTU Tablet and Inform your doctor if you develop symptoms of liver damage such as abdominal pain, loss of appetite, darkened urine or yellow... View More
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
descriptionBrief Description

Indication

Hyperthyroidism

Administration

Should be taken with food.

Adult Dose

Oral Hyperthyroidism Adult: 150-450 mg daily in divided doses. For severe cases, initial doses of 600-1200 mg daily have been used. Maintenance dose f... View More

Child Dose

Oral Hyperthyroidism Child: Neonates: 2.5-5 mg/kg bid; 1 mth-1 yr: 2.5 mg/kg tid; 1-5 yr: 25 mg tid; 5-12 yr: 50 mg tid; 12-18 yr: 100 mg tid.

Renal Dose

Renal impairment: CrCl (ml/min) Dosage Recommendation <10 Reduce dose by 50%. 10-50 Reduce dose by 25%.

Contraindication

Hypersensitivity, pregnancy, lactation.

Mode of Action

Propylthiouracil inhibits the production of thyroid hormones by preventing iodine from being oxidised in the thyroid gland. It also blocks the periphera... View More

Precaution

Reserve use for patients unable to tolerate any other treatments e.g. methimazole, radioactive iodine or surgery. Inform patient of liver failure risk a... View More

Side Effect

Mild leukopenia, lupus-like syndrome, cutaneous vasculitis, thrombocytopenia. Skin rash, urticaria, arthralgia and fever. GI discomfort, vomiting, heada... View More

Interaction

May potentiate activity of anticoagulants. Doses of β-blockers, digitalis glycosides and theophylline may need to be reduced when patient becomes euthyr... View More

descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More