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It is not known whether it is safe to consume alcohol with PTU 50. Please consult your doctor.
PTU 50 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in so... View More
PTU 50 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not har... View More
It is not known whether PTU 50 alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and reac... View More
PTU 50 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of PTU 50 may not be needed in thes... View More
There is limited information available on the use of PTU 50 in patients with liver disease. Please consult your doctor.
PTU 50 belongs to a group of medicine called anti-thyroid agents. It is used in the treatment of hyperthyroidism. It works by reducing the production of... View More
Uses of PTU 50
Side effects of PTU 50
- Skin rash
- Hair loss
- Joint stiffness
- Skin pigmentation
- Paresthesia (tingling or pricking sensation)
How to use PTU 50
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. PTU 50 may be taken with o... View More
How PTU 50 works
PTU 50 is an anti-thyroid medication. It works by reducing the amount of thyroid hormones produced by the thyroid gland.
- PTU Tablet is used for the treatment of hyperthyroidism.
- You may have to stop taking it for a while if you are also taking radio-iodine as a treatment for your overactive thyroid.
- It may affect the level of blood cells in your blood. Inform your doctor if you experience symptoms such as unexplained bruising or bleeding, sore throa... View More
- Stop taking PTU Tablet and Inform your doctor if you develop symptoms of liver damage such as abdominal pain, loss of appetite, darkened urine or yellow... View More
- Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
Should be taken with food.
Oral Hyperthyroidism Adult: 150-450 mg daily in divided doses. For severe cases, initial doses of 600-1200 mg daily have been used. Maintenance dose f... View More
Oral Hyperthyroidism Child: Neonates: 2.5-5 mg/kg bid; 1 mth-1 yr: 2.5 mg/kg tid; 1-5 yr: 25 mg tid; 5-12 yr: 50 mg tid; 12-18 yr: 100 mg tid.
Renal impairment: CrCl (ml/min) Dosage Recommendation <10 Reduce dose by 50%. 10-50 Reduce dose by 25%.
Hypersensitivity, pregnancy, lactation.
Mode of Action
Propylthiouracil inhibits the production of thyroid hormones by preventing iodine from being oxidised in the thyroid gland. It also blocks the periphera... View More
Reserve use for patients unable to tolerate any other treatments e.g. methimazole, radioactive iodine or surgery. Inform patient of liver failure risk a... View More
Mild leukopenia, lupus-like syndrome, cutaneous vasculitis, thrombocytopenia. Skin rash, urticaria, arthralgia and fever. GI discomfort, vomiting, heada... View More
May potentiate activity of anticoagulants. Doses of β-blockers, digitalis glycosides and theophylline may need to be reduced when patient becomes euthyr... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More