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Centoxin0.25mcg

Tablet
rx_reqRequire Prescription
Opsonin Pharma Limited
Generic: Digoxin
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
It is unsafe to consume alcohol with Centoxin.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Centoxin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developin... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Centoxin is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not h... View More
DrivingDriving
UNSAFE
Centoxin may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. .
KidneyKidney
CAUTION
Centoxin should be used with caution in patients with kidney disease. Dose adjustment of Centoxin may be needed. Please consult your doctor. Regular mon... View More
LiverLiver
SAFE IF PRESCRIBED
Centoxin is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Centoxin may not be needed in t... View More
descriptionMedical Overview

Introduction

Centoxin is a medicine used for the treatment of heart failure in combination with other medicines. It helps to provide symptomatic relief by making the... View More

Uses of Centoxin

  • Heart failure
  • Arrhythmia

Side effects of Centoxin

Common
  • Visual impairment
  • Skin rash
  • Nausea
  • Vomiting
  • Diarrhea
  • Dizziness
  • Arrhythmia (irregular heartbeats)

How to use Centoxin

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Centoxin may be taken with... View More

How Centoxin works

Centoxin is a cardiac glycoside. It works by correcting irregular heartbeat to a normal rhythm and increases the force with which the heart muscle contr... View More

What if you forget to take Centoxin?

If you miss a dose of Centoxin, skip it and continue with your normal schedule. Do not double the dose.

quick tipsQuick Tips
  • Take Centoxin at the same time every day.
  • Notify your doctor about other medicines you're taking to avoid drug interactions.
  • Symptoms of overdose include slow heartbeat, dizziness, lightheadedness and breathing problems.
  • Do not discontinue use without consulting your doctor even if you feel better. Stopping abruptly could worsen your condition.
descriptionBrief Description

Indication

Heart failure, Supraventricular arrhythmias, Atrial fibrillation and Atrial flutter

Administration

May be taken with or without food.

Adult Dose

Atrial Fibrillation Rapid digitalizing (loading-dose) regimen PO: 10-15 mcg/kg total loading dose; administer 50% initially; then may cautiously give ... View More

Child Dose

Heart Failure/Atrial Fibrillation Use doses at the lower end of the spectrm when treating heart failure Reduce dose by 20-25% when changing from oral ... View More

Renal Dose

Use lower end of dosing (0.125 mg/day) in patients with impaired renal function

Contraindication

Digitalis toxicity, ventricular tachycardia/fibrillation, obstructive cardiomyopathy. Arrhythmias due to accessory pathways (e.g. Wolff-Parkinson-White ... View More

Mode of Action

Digoxin is a cardiac glycoside which has positive inotropic activity characterized by an increase in the force of myocardial contraction. It also reduce... View More

Precaution

Cardiac dysrhythmias, hypokalaemia, hypertension, IHD, hypercalcaemia, hypomagnesaemia, electroconversion, chronic cor pulmonale, aortic valve disease, ... View More

Side Effect

1-10% Dizziness (4.9%),Mental disturbances (4.1%),Diarrhea (3.2%),Headache (3.2%),Nausea (3.2%),Vomiting (1.6%),Maculopapular rash (1.6%) <1% Anore... View More

Pregnancy Category Note

Pregnancy Experience with digoxin in pregnant women over several decades, based on published retrospective clinical studies and case reports, has not l... View More

Interaction

Effectiveness reduced by phenytoin, neomycin, sulphasalazine, kaolin, pectin, antacids and in patients receiving radiotherapy. Metoclopramide may alter ... View More

descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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