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Darboren 6060mcg/.3ml

Injection
rx_reqRequire Prescription
Square Pharmaceuticals Ltd.
Generic: Darbepoetin alfa
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MRP
5500.00
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Darboren 60. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Darboren 60 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the develo... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Darboren 60 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.... View More
DrivingDriving
SAFE
Darboren 60 does not usually affect your ability to drive.
KidneyKidney
SAFE IF PRESCRIBED
Darboren 60 is safe to use in patients with kidney disease. No dose adjustment of Darboren 60 is recommended.
LiverLiver
CAUTION
Darboren 60 should be used with caution in patients with liver disease. Dose adjustment of Darboren 60 may be needed. Please consult your doctor.
descriptionMedical Overview

Introduction

Darboren 60 is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. It works by stimulating the bone ma... View More

Uses of Darboren 60

  • Anemia due to chronic kidney disease
  • Anemia due to cancer chemotherapy

Side effects of Darboren 60

Common
  • High blood pressure
  • Hypersensitivity

How to use Darboren 60

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Darboren 60 works

Darboren 60 is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood... View More

What if you forget to take Darboren 60?

If you miss a dose of Darboren 60, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to yo... View More

quick tipsQuick Tips
  • Darboren 60 helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
  • It is given as a single injection under your skin.
  • Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells and electrolytes such as potassium in your blood.
  • Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe... View More
  • Stop taking Darboren 60 and inform your doctor if you develop shortness of breath or skin rash.
descriptionBrief Description

Indication

Anaemia of chronic renal failure, Anaemia in chemotherapy patients

Adult Dose

Chronic Kidney Disease-Associated Anemia CKD not on dialysis Recommended starting dose: 0.45 mcg/kg IV/SC q4weeks Consider initiating ESA treatme... View More

Child Dose

Chronic Kidney Disease-Associated Anemia Initiate treatment when the hemoglobin level is <10 g/dL If the hemoglobin level approaches or exceeds 12 g/d... View More

Renal Dose

Chronic Kidney Disease-Associated Anemia CKD not on dialysis Recommended starting dose: 0.45 mcg/kg IV/SC q4weeks Consider initiating ESA treatme... View More

Contraindication

Hypersensitivity, uncontrolled hypertension.

Mode of Action

Darbepoetin alfa is a biosynthetic form of erythropoietin. Recombinant human erythropoietin with sialic acid additions to enhance stability; stimulates ... View More

Precaution

Hypertension; history of seizures; hepatic impairment; sickle cell anaemia; sudden stabing migraine-like pain (warning sign of hypotensive crisis); excl... View More

Side Effect

>10% Cancer patients Fatigue (33%),Diarrhea (22%),Edema (21%),Fever (19%),Dizziness (14%),Arthralgia (13%),Headache (12%),Death (10%) Chronic renal... View More

Pregnancy Category Note

Pregnancy Limited available data on pregnant women are insufficient to determine a drug-associated risk of major birth defects or miscarriage; in anima... View More

Interaction

Antagonism of hypotensive effect and increased risk of hyperkalemia with ACE inhibitors and angiotensin II receptor antagonists. Ethanol.

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More