Certican0.25mg
Tablet
Novartis (Bangladesh) Ltd.
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| Alcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Certican. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Certican is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in ... View More |
| Breastfeeding | CONSULT YOUR DOCTOR Certican is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. |
| Driving | UNSAFE Certican may cause side effects which could affect your ability to drive.
As fatigue is a common side effect with Certican and this may affect your abil... View More |
| Kidney | SAFE IF PRESCRIBED Certican is safe to use in patients with kidney disease. No dose adjustment of Certican is recommended. |
| Liver | CAUTION Certican should be used with caution in patients with liver disease. Dose adjustment of Certican may be needed. Please consult your doctor.
Use of Certi... View More |
Introduction
Certican is used for the prevention of organ rejection in transplant patients. It regulates the body’s immune response, so the body can accept the new o... View More
Uses of Certican
- Breast cancer
- Pancreatic cancer
- Lung cancer
- Kidney cancer
Side effects of Certican
- Weakness
- Sinus inflammation
- Infection
- Fever
- Cough
- Fatigue
- Stomatitis (Inflammation of the mouth)
- Otitis media (infection of ear)
- Diarrhea
- Upper respiratory tract infection
How to use Certican
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Certican may be taken with... View More
How Certican works
Certican suppresses the activity of body's immune system and prevents rejection of the transplanted organ.
- Do not start everolimus and consult your doctor if you have liver problems, diabetes, high blood cholesterol, had a recent surgery or have unhealed woun... View More
- Seek medical advice if you have increased thirst or increased frequency of urination, if you get any infection, suffer from shortness of breath, cough o... View More
- Everolimus may affect male or female fertility; consult your doctor if you are planning to have a child.
- Do not drive or operate machinery while taking everolimus as it may cause fatigue.
Indication
Breast cancer, Kidney cancer, Renal transplant, Liver transplant, Neuroendocrine tumors, Renal cell carcinoma, Astrocytoma, Renal angiomyolipoma,Tuberou... View More
Administration
May be taken with or without food. Administer consistently with food or consistently without food.
Adult Dose
Oral Breast Cancer, Renal Cell Carcinoma, Renal Angiomyolipomas with TSC, Advanced Neuroendocrine Tumors 10 mg once daily with or without food
Contraindication
Patients with hypersensitivity to the active substance, to other rapamycin derivatives, or to any of the excipients. Hypersensitivity reactions manifest... View More
Mode of Action
Everolimus, a proliferation signal inhibitor, prevents allograft rejection in rodent and nonhuman primate models of allotransplantation. It exerts its i... View More
Precaution
Patients taking concomitant ACE inhibitor therapy may be at increased risk for angioedema Interstitial lung disease/noninfectious pneumonitis; monitor ... View More
Side Effect
>10% Stomatitis (44%),Constipation (38%),Infections (37%),Asthenia (33%),Fatigue (31%),Cough (30%),Diarrhea (30%),Rash (29%),Anemia (26%),Nausea (26%),... View More
Pregnancy Category Note
Pregnancy Based on animal studies and mechanism of action therapy can cause fetal harm when administered to pregnant woman; there are limited case repo... View More
Interaction
CYP3A4 inhibitors &/or inducers, CYP2D6 substrates w/ narrow therapeutic index, PgP inhibitors, rifampicin, ACE inhibitors, grapefruit juice & live vacc... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More