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Sinapride 11mg

Tablet
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The Ibn Sina Pharmaceutical Ind. Ltd.
Generic: Prucalopride
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sinapride 1. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Sinapride 1 during pregnancy is not available. Please consult your doctor.
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Sinapride 1 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
DrivingDriving
UNSAFE
Sinapride 1 may cause side effects which could affect your ability to drive. Sinapride 1 may cause dizziness and tiredness, especially on the first day ... View More
KidneyKidney
CAUTION
Sinapride 1 should be used with caution in patients with severe kidney disease. Dose adjustment of Sinapride 1 may be needed. Please consult your doctor... View More
LiverLiver
CAUTION
Sinapride 1 should be used with caution in patients with severe liver disease. Dose adjustment of Sinapride 1 may be needed. Please consult your doctor.... View More
descriptionMedical Overview

Introduction

Sinapride 1 is a prescription medicine used in the treatment of constipation. It increases the release of certain chemical that improves the movement of... View More

Uses of Sinapride 1

  • Constipation

Side effects of Sinapride 1

Common
  • Headache
  • Nausea
  • Diarrhea
  • Abdominal pain

How to use Sinapride 1

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sinapride 1 may be taken w... View More

How Sinapride 1 works

Sinapride 1 indirectly stimulates the release of acetylcholine, a chemical messenger that can increase the motility of the intestine.

What if you forget to take Sinapride 1?

If you miss a dose of Sinapride 1, skip it and continue with your normal schedule. Do not double the dose.

quick tipsQuick Tips
  • Sinapride 1 helps treat chronic constipation and improve bowel movements, when laxatives have failed to provide adequate relief.
  • It can be taken with or without food, at any time of the day.
  • It may cause diarrhea. Drink plenty of water and inform your doctor if it bothers you.
  • Inform your doctor if your constipation has not improved even after four weeks of taking this medication.
descriptionBrief Description

Indication

Chronic idiopathic constipation.

Administration

May be taken with or without food.

Adult Dose

Oral Chronic idiopathic constipation Adult: 2 mg once daily. Elderly: Initially, 1 mg once daily, may increase to 2 mg once daily if necessary. He... View More

Renal Dose

Severe (GFR <30 mL/min/1.73 m2): 1 mg once daily. Patient on dialysis: Contraindicated.

Contraindication

Intestinal obstruction or perforation, obstructive ileus, active severe inflammatory bowel conditions (e.g. Crohn’s disease, toxic megacolon/megarectum,... View More

Mode of Action

Prucalopride is a selective 5-HT4 receptor agonist w/ prokinetic effect. It stimulates peristaltic reflex, intestinal secretions, and GI motility.

Precaution

Patient w/ history of arrhythmias or ischaemic CV disease, severe and unstable concomitant disease (e.g. cancer, AIDS, neurological or psychiatric, pulm... View More

Side Effect

Nervous: Headache, dizziness, fatigue, malaise, tremors. CV: Palpitations. GI: Nausea, abdominal pain and distention, diarrhoea, vomiting, flatulence,... View More

Interaction

May decrease serum concentration of contraceptives (i.e. oestrogens, progestins). May enhance adverse effect of levosulpiride. Increased serum concentra... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More