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Daconib 4545mg

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Everest Pharmaceuticals Ltd.
Generic: Dacomitinib
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descriptionMedical Overview


Non-small Cell Lung Cancer


Administer with or without food at the same time each day

Adult Dose

Non-small Cell Lung Cancer Indicated for first-line treatment of patients with metastatic non-small lung cancer (NSCLC) with epidermal growth factor re... View More

Renal Dose

Renal impairment Mild or moderate (CrCl 30-89 mL/min estimated by Cockcroft-Gault equation): No dosage adjustment necessary Severe (CrCl <30 mL/min): ... View More

Mode of Action

Irreversible kinase inhibitor of the human EGFR family (EGFR/HER1, HER2, and HER4) and certain EGFR-activating mutations (exon 19 deletion or the exon 2... View More


Severe and fatal ILD/pneumonitis occurred; monitor for pulmonary symptoms indicative of ILD/pneumonitis; withhold treatment and promptly investigate for... View More

Side Effect

>10% (All Grades) Diarrhea (87%) Rash (69%) Paronychia (64%) Stomatitis (45%) Anemia (44%) Hypoalbuminemia (44%) Lymphopenia (42%) ... View More

Pregnancy Category Note

Pregnancy Based on findings from animal studies and its mechanism of action, fetal harm may occur when administered to a pregnant woman There are no... View More

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More