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Niloren200mg

Capsule
rx_reqRequire Prescription
Renata Limited
Generic: Nilotinib
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descriptionSafety Advices
AlcoholAlcohol
SAFE
Consuming alcohol with Niloren does not cause any harmful side effects.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Niloren is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in s... View More
BreastfeedingBreastfeeding
UNSAFE
Niloren is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
DrivingDriving
UNSAFE
Niloren may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
KidneyKidney
SAFE IF PRESCRIBED
Niloren is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Niloren may not be needed in th... View More
LiverLiver
CAUTION
Niloren should be used with caution in patients with liver disease. Dose adjustment of Niloren may be needed. Please consult your doctor.
descriptionMedical Overview

Introduction

Niloren is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medic... View More

Uses of Niloren

  • Blood cancer (Chronic myeloid leukaemia)

Side effects of Niloren

Common
  • Headache
  • Nausea
  • Abdominal pain
  • Rash
  • Itching
  • Hair loss
  • Muscle pain
  • Fatigue

How to use Niloren

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Niloren is to be taken empty stomach.

How Niloren works

Niloren is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop ... View More

What if you forget to take Niloren?

If you miss a dose of Niloren, skip it and continue with your normal schedule. Do not double the dose.

quick tipsQuick Tips
  • Niloren is used for the treatment of thyroid cancer.
  • Take it with or without food, preferably at the same time each day.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
  • Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe... View More
  • It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
  • Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
descriptionBrief Description

Indication

Chronic myelogenous leukaemia

Administration

Should be taken on an empty stomach. Avoid food at least 2 hr before & at least 1 hr after a dose. Swallow whole, do not chew/crush. Avoid grapefruit pr... View More

Adult Dose

Oral Chronic Myeloid Leukemia (CML), Newly Diagnosed Indicated for initial treatment of newly diagnosed Philadelphia chromosome positive chronic phase... View More

Child Dose

<18 years old: Not recommended

Contraindication

Patients with hypokalaemia, hypomagnaesemia or long QT syndrome. Pregnancy.

Mode of Action

Nilotinib is a potent inhibitor of BCR-ABL tyrosine kinase. It binds to and stabilises the inactive conformation of the kinase domain of Abl protein.

Precaution

Patient w/ history of pancreatitis, w/ total gastrectomy. Hepatic impairment. Maintain adequate hydration and correct uric acid levels, hypomagnesaemia,... View More

Side Effect

>10% Rash (33%),Headache (31%),Nausea (31%),Pruritus (29%),Fatigue (28%),Pyrexia (24%),Diarrhea (22%),Constipation (21%),Vomiting (21%),Arthralgia (18%... View More

Interaction

Drugs that inhibit gastric acid secretion (e.g. PPIs) may reduce solubility and bioavailability of nilotinib. Potentially Fatal: Concomitant use w/ p... View More

descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More