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Ragil 0.50.5mg

Tablet
rx_reqRequire Prescription
Eskayef Pharmaceuticals Ltd.
Generic: Rasagiline
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135.00
MRP
150.00
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
It is unsafe to consume alcohol with Ragil 0.5.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Ragil 0.5 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developi... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Ragil 0.5 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
DrivingDriving
UNSAFE
Ragil 0.5 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
KidneyKidney
SAFE IF PRESCRIBED
Ragil 0.5 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Ragil 0.5 may not be needed i... View More
LiverLiver
CAUTION
Ragil 0.5 should be used with caution in patients with liver disease. Dose adjustment of Ragil 0.5 may be needed. Please consult your doctor. Use of Rag... View More
descriptionMedical Overview

Introduction

Ragil 0.5 is a medicine used to treat Parkinson's disease. It helps to provide better control of body movements and prevents excessive shaking and stiff... View More

Uses of Ragil 0.5

  • Parkinson's disease

Side effects of Ragil 0.5

Common
  • Joint pain
  • Insomnia (difficulty in sleeping)
  • Indigestion
  • Flu-like symptoms
  • Depression
  • Cough
  • Peripheral edema

How to use Ragil 0.5

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ragil 0.5 may be taken wit... View More

How Ragil 0.5 works

Ragil 0.5 works by increasing the amount of dopamine, a chemical messenger that is needed to control movement in the brain.

quick tipsQuick Tips
  • You have been prescribed Ragil 0.5 to treat your symptoms of Parkinson's disease.
  • It can be taken with or without food or as directed by your doctor.
  • Be cautious while driving or doing anything that requires concentration as Ragil 0.5 can make you very sleepy.
  • Ragil 0.5 can make you dizzy or lightheaded, especially when you suddenly stand up from sitting or laying down.
  • Let your doctor know if you are also taking medicines for depression or mood disorders.
  • Do not stop taking Ragil 0.5 suddenly. Sudden stopping may cause confusion, stiff muscles and a high fever.
  • As a precaution, foods high in tyramine (e.g. aged cheeses, air-dried meat, soy sauce, tap/draft beers and red wine) should be avoided when taking Ragil... View More
descriptionBrief Description

Indication

Parkinson Disease

Administration

May be taken with or without food. Avoid tyramine-rich foods, beverages or dietary supplements & amines (from cough/cold prep).

Adult Dose

Parkinson Disease Monotherapy: 1 mg PO qDay Adjunct without levodopa: 1 mg PO qDay Adjunct to levodopa: 0.5 mg PO qDay initially, may increase to 1 m... View More

Child Dose

<18 years: Safety and efficacy not established

Renal Dose

Renal impairment: No dosage adjustment required for mild-to-moderate; not studied in severe

Contraindication

Severe hepatic impairment. Concomitant use w/ other MAOIs and pethidine w/in 14 days after discontinuation of therapy; St John's wort.

Mode of Action

Rasagiline is a potent, irreversible monoamine oxidase (MAO)-B selective inhibitor which may cause an increase in extracellular levels of dopamine in th... View More

Precaution

May cause hypertension (including severe hypertensive syndromes) at recommended doses May exacerbate hypertension; antihypertensive drugs may require d... View More

Side Effect

>10% EPS (dyskinesia/dystonia) (18%) Headache (14%) Nausea (10-12%) 1-10% Postural hypotension (6-9%) Constipation (4-9%) Weight loss (2-9%) A... View More

Interaction

Increased plasma levels w/ potent CYP1A2 inhibitors (e.g. ciprofloxacin). Increased clearance w/ entacapone. Potentially Fatal: Increased risk of non-s... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More