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Ragil 11mg

Tablet
rx_reqRequire Prescription
Eskayef Pharmaceuticals Ltd.
Generic: Rasagiline
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Best Price
180.00
MRP
200.00
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
It is unsafe to consume alcohol with Ragil 1.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Ragil 1 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Ragil 1 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
DrivingDriving
UNSAFE
Ragil 1 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
KidneyKidney
SAFE IF PRESCRIBED
Ragil 1 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Ragil 1 may not be needed in th... View More
LiverLiver
CAUTION
Ragil 1 should be used with caution in patients with liver disease. Dose adjustment of Ragil 1 may be needed. Please consult your doctor. Use of Ragil 1... View More
descriptionMedical Overview

Introduction

Ragil 1 is a medicine used to treat Parkinson's disease. It helps to provide better control of body movements and prevents excessive shaking and stiffne... View More

Uses of Ragil 1

  • Parkinson's disease

Side effects of Ragil 1

Common
  • Joint pain
  • Insomnia (difficulty in sleeping)
  • Indigestion
  • Flu-like symptoms
  • Depression
  • Cough
  • Peripheral edema

How to use Ragil 1

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ragil 1 may be taken with ... View More

How Ragil 1 works

Ragil 1 works by increasing the amount of dopamine, a chemical messenger that is needed to control movement in the brain.

quick tipsQuick Tips
  • You have been prescribed Ragil 1 to treat your symptoms of Parkinson's disease.
  • It can be taken with or without food or as directed by your doctor.
  • Be cautious while driving or doing anything that requires concentration as Ragil 1 can make you very sleepy.
  • Ragil 1 can make you dizzy or lightheaded, especially when you suddenly stand up from sitting or laying down.
  • Let your doctor know if you are also taking medicines for depression or mood disorders.
  • Do not stop taking Ragil 1 suddenly. Sudden stopping may cause confusion, stiff muscles and a high fever.
  • As a precaution, foods high in tyramine (e.g. aged cheeses, air-dried meat, soy sauce, tap/draft beers and red wine) should be avoided when taking Ragil... View More
descriptionBrief Description

Indication

Parkinson Disease

Administration

May be taken with or without food. Avoid tyramine-rich foods, beverages or dietary supplements & amines (from cough/cold prep).

Adult Dose

Parkinson Disease Monotherapy: 1 mg PO qDay Adjunct without levodopa: 1 mg PO qDay Adjunct to levodopa: 0.5 mg PO qDay initially, may increase to 1 m... View More

Child Dose

<18 years: Safety and efficacy not established

Renal Dose

Renal impairment: No dosage adjustment required for mild-to-moderate; not studied in severe

Contraindication

Severe hepatic impairment. Concomitant use w/ other MAOIs and pethidine w/in 14 days after discontinuation of therapy; St John's wort.

Mode of Action

Rasagiline is a potent, irreversible monoamine oxidase (MAO)-B selective inhibitor which may cause an increase in extracellular levels of dopamine in th... View More

Precaution

May cause hypertension (including severe hypertensive syndromes) at recommended doses May exacerbate hypertension; antihypertensive drugs may require d... View More

Side Effect

>10% EPS (dyskinesia/dystonia) (18%) Headache (14%) Nausea (10-12%) 1-10% Postural hypotension (6-9%) Constipation (4-9%) Weight loss (2-9%) A... View More

Interaction

Increased plasma levels w/ potent CYP1A2 inhibitors (e.g. ciprofloxacin). Increased clearance w/ entacapone. Potentially Fatal: Increased risk of non-s... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More