Resp distress syndrome (RDS) in premature infants.

Indication

Prevention in premature infant <1250 g birthwt or w/ evidence of surfactant deficiency 
Preferably w/in 15 mins of birth. 
Rescue Preferably by 8 hr of age.

4 mL/kg birth wt(100 mg of phospholipids/kg birth wt) intratracheally up to 4 doses in 1st 48 hr. 

Doses should not be given more frequently than 6 hrly. To be administered as soon as possible. 

Child Dose

Contraindication

Natural bovine pulmonary surfactant; replaces deficient endogenous lung surfactant in neonates with respiratory distress syndrome.

Surfactant prevents the alveoli from collapsing during expiration by lowering surface tension between alveolar surfaces and air.

Mode of Action

Infants <600 g birth wt. For intratracheal use only.

Precaution

Transient bradycardia. O2 desaturation, endotracheal tube reflux & blockage, pallor, vasoconstriction, hypotension, HTN, hypocarbia, hypercarbia & apnea.

Alveofact45mg/ml

Injection

ZAS Corporation

Additional Offers