Cisplatin Hexal PI is used in the treatment of ovarian, cervical and testicular cancer. It shows its working by stopping or slowing down the growth of c... View More
Uses of Cisplatin Hexal PI
Side effects of Cisplatin Hexal PI
How to use Cisplatin Hexal PI
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
How Cisplatin Hexal PI works
Cisplatin Hexal PI is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth an... View More
What if you forget to take Cisplatin Hexal PI?
If you miss a dose of Cisplatin Hexal PI, please consult your doctor.
Lymphomas, Sarcomas, Carcinomas, Small cell lung cancer, Ovarian cancer, Germ cell tumors, Metastatic Testicular Tumors, Metastatic Ovarian Tumors, Adva... View More
IV Preparation Further dilution stability is dependent on chloride ion concentration & should be mixed in solutions of NS (at least 0.3% NaCl) Further... View More
Metastatic Testicular Tumors Usual dose in combination with other approved chemotherapeutic agents is 20 mg/m²/day IV for 5 days/cycle Pretreatment h... View More
Renal Impairment CrCl 10-50 mL/min: Decrease dose 50% CrCl <10 mL/min: Contraindicated
Patients with severe renal or auditory disorder, known hypersensitivity, severe bone marrow suppression, peripheral neuropathy, pregnancy, lactation.
Mode of Action
Cisplatin modifies cell cycle by interfering with DNA structure and function. Effects are most prominent during the S phase but cells are killed at all ... View More
Patients with renal or hepatic disorder, myelosuppression. Monitor renal, neurological and auditory function. Perform blood counts regularly. Maintain a... View More
>10% Nausea (76-100%),Vomiting (76-100%),Nephrotoxicity (28-36%),Ototoxicity, especially in children (31%),Myelosuppression (25-30%),Anaphylaxis (1-20%... View More
Pregnancy Category Note
Pregnancy Based on human data from published literature, cisplatin can cause fetal harm when administered to pregnant women; data demonstrates transpla... View More
Synergistic with 5-fluorouracil and etoposide. Efficacy increased and toxicity reduced when combined with radioprotecting agent WR 2721. At doses ?100 m... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More