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Olpres HZ 4012.5mg+40mg

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Ziska Pharmaceuticals Ltd.
Generic: Hydrochlorothiazide + Olmesartan Medoxomil
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descriptionSafety Advices
Olpres HZ 40 may cause excessive drowsiness with alcohol.
Olpres HZ 40 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it... View More
Olpres HZ 40 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby... View More
Olpres HZ 40 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Olpres HZ 40 should be used with caution in patients with severe kidney disease. Dose adjustment of Olpres HZ 40 may be needed. Please consult your doct... View More
Olpres HZ 40 should be used with caution in patients with liver disease. Dose adjustment of Olpres HZ 40 may be needed. Please consult your doctor.
descriptionMedical Overview


Olpres HZ 40 is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated it can ... View More

Uses of Olpres HZ 40

  • Hypertension (high blood pressure)

Side effects of Olpres HZ 40

  • Nausea
  • Taste change
  • Upset stomach
  • Diarrhea
  • Headache
  • Dizziness
  • Weakness
  • Electrolyte imbalance
  • Glucose intolerance
  • Increased blood lipid level
  • Increased blood uric acid
  • Decreased blood pressure

How to use Olpres HZ 40

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Olpres HZ 40 may be taken ... View More

How Olpres HZ 40 works

Olpres HZ 40 is a combination of two medicines: Hydrochlorothiazide and olmesartan which lower blood pressure effectively. Hydrochlorothiazide is a diur... View More

quick tipsQuick Tips
  • You have been prescribed Olpres HZ 40 for the treatment of high blood pressure.
  • It can be taken with or without food.
  • Olpres HZ 40 may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle weakness.
  • It may cause dizziness. Get up slowly when rising from a sitting or lying position.
  • Use of Olpres HZ 40 during pregnancy or breastfeeding is unsafe.
  • It may also decrease the risk of stroke and heart attacks.
descriptionBrief Description


Hypertension, Diabetic nephropathy


May be taken with or without food.

Adult Dose

Hypertension Initial: 20 mg/12.5 mg PO qDay May increase to 40 mg/25 mg after 2 weeks Hepatic Impairment Dose adjustment not necessary

Child Dose

Safety and efficacy not established

Renal Dose

Renal Impairment CrCl <30 mL/min: Not recommended


Hypersensitivity to olmesartan medoxomil, hydrochlorothiazide or to other sulfonamide-derived drugs. Severe hepatic & renal impairment (CrCl <30 mL/min)... View More

Mode of Action

Hydrochlorothiazide inhibits the reabsorption of Na and chloride in the distal tubules causing increased excretion of Na and water K and hydrogen ions. ... View More


Drugs that act on renin-angiotensin system can cause fetal injury and death when used in 2nd and 3rd trimesters of pregnancy. Olmesartan medoxomil shoul... View More

Side Effect

1-10% Olmesartan Dizziness (3%),Headache (1%),Fatigue,Diarrhea (1%),Hyperglycemia (1%),Hypertriglyceridemia (1%),Back pain (1%),Bronchitis (1%),Flu-li... View More

Pregnancy Category Note

Pregnancy Category: C (1st trimester); D (2nd & 3rd trimesters)


Olmesartan medoxomil: Increased risk of hypotension, hyperkalemia & changes in renal function w/ aliskiren. May result in deterioration of renal functio... View More

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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