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Clofranil 25
Clofranil 25
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Clofranil 2525mg

Tablet
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Sun Pharmaceutical (Bangladesh) Ltd.
Generic: Clomipramine Hydrochloride
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51.30
MRP
55.20
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
It is unsafe to consume alcohol with Clofranil 25.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Clofranil 25 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the devel... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Clofranil 25 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
DrivingDriving
UNSAFE
Clofranil 25 may cause side effects which could affect your ability to drive. If you feel dizzy, tired, have blurred vision, have difficulty concentrati... View More
KidneyKidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Clofranil 25 in patients with kidney disease. Please consult your doctor. Caution should be exercis... View More
LiverLiver
CAUTION
Clofranil 25 should be used with caution in patients with liver disease. Dose adjustment of Clofranil 25 may be needed. Please consult your doctor. Regu... View More
descriptionMedical Overview

Introduction

Clofranil 25 is a tricyclic antidepressant. It is used in adults to treat Obsessive-Compulsive Disorder (OCD). It also treats muscular weakness (cataple... View More

Uses of Clofranil 25

  • Obsessive-compulsive disorder

Side effects of Clofranil 25

Common
  • Altered libido
  • Constipation
  • Dryness in mouth
  • Ejaculation disorder
  • Sleepiness
  • Difficulty in urination

How to use Clofranil 25

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clofranil 25 is to be take... View More

How Clofranil 25 works

Clofranil 25 is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depre... View More

What if you forget to take Clofranil 25?

If you miss a dose of Clofranil 25, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to y... View More

quick tipsQuick Tips
  • It may take 4 to 6 weeks for Clofranil 25 to start working. Keep taking it as prescribed.
  • It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Clofranil 25 as it may cause excessive sleepiness.
  • Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
descriptionBrief Description

Indication

Depression, Panic disorder, Obsessive compulsive disorder, Cataplexy, Narcolepsy, Phobias, Premature ejaculation, Enuresis, Trichotillomania

Administration

Should be taken with food.

Adult Dose

Oral Adjunct for cataplexy associated with narcolepsy Adult: Initially, 10 mg daily gradually increased to 10-75 mg daily. Elderly: Dose reduction ma... View More

Child Dose

Obsessive-Compulsive Disorder <10 years: Safety and efficacy not established >10 years: 25 mg PO qDay initially Gradually increase to maximum 3 m... View More

Contraindication

Hypersensitivity. Concomitant use of MAOIs; recovery phase following MI, heartblock or other arrhythmias; mania; childn.

Mode of Action

Clomipramine is a potent inhibitor of serotonin re-uptake in the brain. Significant antagonism at cholinergic and ?1-receptors. Weak antagonism at dopam... View More

Precaution

Cardiovascular insufficiency; narrow-angle glaucoma; urinary retention; history of epilepsy; renal or hepatic dysfunction; electroconvulsive therapy; hy... View More

Side Effect

>10% Xerostomia (84%),Headache (50-55%),Constipation (47%),Ejaculation failure (42%),Fatigue (35-40%),Nausea (30-35%),Impotence (20-25%),Weight gain (1... View More

Pregnancy Category Note

Pregnancy Category: C Lactation: distributed in breast milk, do not nurse (AAP states effect on nursing infants is unknown but may be of concern)

Interaction

Barbiturates increase metabolism of tricyclic antidepressants; conversely cimetidine, guanethidine, haloperidol and phenothiazines block the tricyclic m... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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