Doctor's Chemicals Works Ltd.
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Caution is advised when consuming alcohol with Cloles. Please consult your doctor.
Cloles is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effec... View More
Cloles is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Cloles does not usually affect your ability to drive.
SAFE IF PRESCRIBED
Cloles is safe to use in patients with kidney disease. No dose adjustment of Cloles is recommended. However, inform your doctor if you have any underlyi... View More
Cloles should be used with caution in patients with liver disease. Dose adjustment of Cloles may be needed. Please consult your doctor. Use of Cloles is... View More
Cloles belongs to a group of medicines called statins. It is used to lower cholesterol and to reduce the risk of heart disease. Cholesterol is a fatty s... View More
Uses of Cloles
- High cholesterol
- Prevention of heart attack
Side effects of Cloles
- Muscle pain
How to use Cloles
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cloles may be taken with o... View More
How Cloles works
Cloles is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required in the body to make cholesterol. It ... View More
What if you forget to take Cloles?
If you miss a dose of Cloles, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your re... View More
- In general, Cloles is safe. It may cause diarrhea, gas or an upset stomach. If any of these happen to you, take it with food.
- Inform your doctor if you experience fatigue, muscle weakness or muscle pain.
- Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of liver proble... View More
- Inform your doctor if you have kidney disease, liver disease or diabetes before starting treatment with this medicine. If you are diabetic, monitor your... View More
- Do not take Cloles if you are pregnant, planning a pregnancy or breastfeeding.
Oral Mixed dyslipidaemia, Heterozygous familial hypercholesterolaemia, Nonfamilial hypercholesterolaemia Adult: Initially, 10 or 20 mg once daily, may... View More
May increase risk of myopathy and rhabdomyolysis w/ CYP3A4 potent inhibitor (e.g. HIV or HCV protease inhibitors, itraconazole, clarithromycin), fenofib... View More
Patients who consume substantial quantities of alcohol. History of liver disease. Patients with risk factors for myopathy or rhabdomyolysis. Hypothyroid... View More
Atorvastatin competitively inhibits HMG-CoA reductase, the enzyme that catalyses the conversion of HMG-CoA to mevalonate. This results in the induction ... View More
Oral Mixed dyslipidaemia, Heterozygous familial hypercholesterolaemia, Nonfamilial hypercholesterolaemia Child: Heterozygous familial hypercholesterol... View More
Mode of Action
Atorvastatin can be administered as a single dose at any time of the day, with or without food. Avoid excessive consumption (>1 L/day) of grapefruit jui... View More
Primary hypercholesterolemia (heterozygous familial and nonfamilial), Mixed Dyslipidemia, Homozygous familial hypercholesterolemia, Hypertriglyceridemi... View More
Renal Insufficiency: Renal disease does not affect the plasma concentrations or LDL-C reduction of atorvastatin; thus, dosage adjustment in patients wit... View More
Pregnancy Category Note
>10% Diarrhea (5-14%),Nasopharyngitis (4-13%),Arthralgia (4-12%) 1-10% Insomnia (1-5%),Urinary tract infection (4-8%),Nausea (4-7%),Dyspepsia (3-6%... View More
Hypersensitivity, active liver disease or unexplained persistent elevations of serum transaminase, porphyria, pregnancy, lactation.
Alternative brand for Cloles
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More