Co-Disys 5/80 contains two medicines, both of which help to control high blood pressure. It lowers the blood pressure by relaxing the blood vessels and ... View More
Uses of Co-Disys 5/80
Side effects of Co-Disys 5/80
How to use Co-Disys 5/80
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Co-Disys 5/80 may be taken... View More
How Co-Disys 5/80 works
Co-Disys 5/80 is a combination of two medicines: Amlodipine and Valsartan, which lowers blood pressure effectively. Amlodipine is a calcium channel bloc... View More
Hypertension Initiate with 5 mg/160 mg PO qDay OR Substitute for individually titrated components May increase dose after at least 2 weeks, not t... View More
Amlodipine : Plasma concentrations may be elevated w/ CYP3A4 inhibitors (e.g. azole antifungals, ritonavir). Concomitant therapy w/ simvastatin may incr... View More
Impaired liver or renal function, CHF, sick-sinus syndrome, severe ventricular dysfunction, hypertrophic cardiomyopathy, severe aortic stenosis. Caution... View More
Pregnancy Category: C (1st trimester); D (2nd & 3rd trimesters).
Amlodipine relaxes peripheral and coronary vascular smooth muscle. It produces coronary vasodilation by inhibiting the entry of Ca ions into the slow ch... View More
Mode of Action
May be taken with or without food.
Renal impairment Mild or moderate (CrCl >30 mL/min): Dose adjustment not necessary Severe (CrCl <30 mL/min): Not studied
Pregnancy Category Note
>10% Headache,Increased BUN (6-17%) 1-10% Peripheral edema (5-8%),Anxiety (3%),Nasopharyngitis (4%),Increased potassium (3%),Upper respiratory infe... View More
Known hypersensitivity to dihydropyridines.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More