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The ACME Laboratories Ltd.
Generic: Delafloxacin
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descriptionMedical Overview


Acute bacterial skin and skin structure infections


IV Preparation Reconstitute 300-mg vial with10.5 mL D5W or 0.9% NaCl, resulting in 300 mg/12 mL (25 mg/mL) Shake vial vigorously until contents are ... View More

Adult Dose

Skin and Skin Structure Infections Parenteral 300 mg IV q12hr for 5-14 days, OR 300 mg IV q12hr, then switch to a 450-mg tablet PO q12hr for 5-14 day... View More

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment IV CrCl 30-89 mL/min: No dosage adjustment needed CrCl 15-29 mL/min: 200 mg IV q12hr OR 200 mg IV q12hr, then switch to 450 mg PO q1... View More


Documented hypersensitivity to delafloxacin or its components or other fluoroquinolones

Mode of Action

Fluoroquinolone antibiotic; inhibits both bacterial topoisomerase IV and DNA gyrase (topoisomerase II) enzymes, which are required for bacterial DNA rep... View More


Fluoroquinolones are associated with disabling and potentially irreversible serious adverse reactions from different body systems, including tendinitis,... View More

Side Effect

1-10% Nausea (8%) Diarrhea (8%) Headache (3%) Transaminase elevations (3%) Vomiting (2%) Cardiac disorders: Sinus tachycardia, palpitations, bra... View More

Pregnancy Category Note

Pregnancy Data are limited regarding use in pregnant women and are insufficient to inform a drug-associated risk of major birth defects and miscarriage... View More


Fluoroquinolones form chelates with alkaline earth and transition metal cations Delafloxacin PO administration with antacids containing aluminum or mag... View More

Alternative brand for Delaflox
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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