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Cotrim400mg+80mg

Tablet
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Square Pharmaceuticals Ltd.
Generic: Sulphamethoxazole + Trimethoprim (Co-trimoxazole)
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Cotrim. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Cotrim is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in so... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Cotrim is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not har... View More
DrivingDriving
CONSULT YOUR DOCTOR
It is not known whether Cotrim alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and reac... View More
KidneyKidney
CAUTION
Cotrim should be used with caution in patients with kidney disease. Dose adjustment of Cotrim may be needed. Please consult your doctor. Use of Cotrim i... View More
LiverLiver
CAUTION
Cotrim should be used with caution in patients with liver disease. Dose adjustment of Cotrim may be needed. Please consult your doctor. Use of Cotrim is... View More
descriptionMedical Overview

Introduction

Cotrim is a combination medicine that is used to treat various types of bacterial infections such as pneumonia, bronchitis, infections of urinary tract,... View More

Uses of Cotrim

  • Bacterial infections

Side effects of Cotrim

Common
  • Nausea
  • Vomiting
  • Skin rash
  • Allergic reaction

How to use Cotrim

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and ta... View More

How Cotrim works

Cotrim is a combination of two antibiotics: Sulfamethoxazole and Trimethoprim. These antibiotics work by preventing the bacteria from producing folic ac... View More

quick tipsQuick Tips
  • You have been prescribed Cotrim for the treatment of many types of bacterial infections.
  • Finish the prescribed course of Cotrim, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your st... View More
  • Stop taking Cotrim and inform your doctor if you develop skin rash/blisters or other unexplained skin reaction while taking Cotrim.
  • In case of long-term use, have regular monthly blood tests to monitor your blood cells as suggested by your doctor.
descriptionBrief Description

Indication

Upper and lower respiratory tract infections, Gastrointestinal tract infections, Renal and urinary tract infections, Skin and wound infections, Septicae... View More

Adult Dose

Oral Acute exacerbations of chronic bronchitis ; Acute otitis media; Urinary tract infections, GI infections; Resp and urinary tract infections; Suscep... View More

Child Dose

Child: Oral 8–10 mg TMP/kg/day q12h 2 mg TMP/kg/day for UTI prophylaxis q24h 15–20 mg TMP/kg/day for Pneumocystis (carinii) jiroveci pneumonia ... View More

Renal Dose

Renal impairment: CrCl (ml/min) Dosage Recommendation <15 Not recommended. 15-30 Half the standard dose.

Contraindication

Known hypersensitivity to trimethoprim or sulfonamides; severe hepatic failure or marked liver parenchymal damage, jaundice; serious haematological diso... View More

Mode of Action

Co-trimoxazole exhibits the synergistic actions of its components (sulfamethoxazole and trimethoprim) by 10-fold. Sulfamethoxazole inhibits dihydrofolic... View More

Precaution

Patient w/ severe allergy, bronchial asthma, thyroid dysfunction. Renal and mild to moderate hepatic impairment. Lactation. Patient Counselling May impa... View More

Side Effect

Allergic myocarditis, erythema multiforme, exfoliative dermatitis, angioedema, drug fever, chills, Henoch-Schoenlein purpura, serum sickness-like syndro... View More

Interaction

Reduced ciclosporin concentrations in blood when used concurrently. Increases toxicity of methotrexate. Inhibits phenytoin clearance. Potentiates warfar... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More