Beacon Pharmaceuticals Ltd.
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It is not known whether it is safe to consume alcohol with Criston 1. Please consult your doctor.
Criston 1 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in... View More
Criston 1 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Criston 1 may cause side effects which could affect your ability to drive.
Criston 1 should be used with caution in patients with kidney disease. Dose adjustment of Criston 1 may be needed. Please consult your doctor.
Criston 1 should be used with caution in patients with liver disease. Dose adjustment of Criston 1 may be needed. Please consult your doctor.
Criston 1 is an anti-cancer medication used in the treatment of breast cancer, non-small cell lung cancer, pancreatic cancer, kidney cancer, blood cance... View More
Uses of Criston 1
- Breast cancer
- Non-small cell lung cancer
- Pancreatic cancer
- Kidney cancer
- Blood cancer
- Multiple myeloma
- Bone cancer
Side effects of Criston 1
- Hair loss
- Peripheral neuropathy (tingling and numbness of feet and hand)
How to use Criston 1
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Criston 1 works
Criston 1 blocks replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells.
- Avoid being near people suffering from infections (such as, cold, flu, contagious illnesses), as you may be more susceptible to infections, while on vin... View More
- Avoid even accidental contamination of eyes with vincristine as it may cause severe irritation.
- Vincristine may cause acute kidney disease (nephropathy) related to uric acid level.
- Care should be taken in elderly patients because they are more susceptible to neurotoxic effects of vincristine.
- In males, vincristine may cause aspermia (lack of semen causing infertility); in females vincristine may cause amenorrhea (absence of menstruation), whi... View More
- Tell your doctor if you are or planning to become pregnant or are breastfeeding.
Acute lymphoblastic leukaemia, Acute myeloid leukaemia, AIDS-related Kaposi's sarcoma, Brain tumours, Hodgkin's disease, Neuroblastoma, Non-Hodgkin's ly... View More
Intravenous Acute lymphoblastic leukaemia Adult: Usual recommended dosage: 1.4-1.5 mg/m2 once wkly. Max: 2 mg wkly. Subsequent doses may be modified b... View More
Intravenous Acute lymphoblastic leukaemia Child: Usual recommended dosage: 1.5-2 mg/m2 once wkly; for patients ?10 kg: Initiate at 0.05 mg/kg once wkl... View More
Renal Impairment Dose adjustment not necessary
Patients with demyelinating form of Charcot-Marie-Tooth syndrome. Pregnancy and lactation. Intrathecal admin (may be fatal). Patients receiving radiatio... View More
Mode of Action
Vincristine arrests cell division at the metaphase stage by inhibiting microtubule formation in the mitotic spindle.
Elderly. Preexisting pulmonary dysfunction or neuromuscular disease; leucopenia or a complicating infection; impaired liver function; obstructive jaundi... View More
>10% Alopecia (20-70%) Frequency Not Defined Dose limiting neurotoxicity (e.g. motor function impairment, gait abnormalities), hyperuricaemia, bron... View More
Decreased digoxin (tablets) and verapamil absorption with antineoplastic regimens. Increased etoposide serum levels with vincristine. Increased toxicity... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More