Criston 1 is an anti-cancer medication used in the treatment of breast cancer, non-small cell lung cancer, pancreatic cancer, kidney cancer, blood cance... View More
Uses of Criston 1
Side effects of Criston 1
How to use Criston 1
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Criston 1 works
Criston 1 blocks replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells.
Acute lymphoblastic leukaemia, Acute myeloid leukaemia, AIDS-related Kaposi's sarcoma, Brain tumours, Hodgkin's disease, Neuroblastoma, Non-Hodgkin's ly... View More
Intravenous Acute lymphoblastic leukaemia Adult: Usual recommended dosage: 1.4-1.5 mg/m2 once wkly. Max: 2 mg wkly. Subsequent doses may be modified b... View More
Intravenous Acute lymphoblastic leukaemia Child: Usual recommended dosage: 1.5-2 mg/m2 once wkly; for patients ?10 kg: Initiate at 0.05 mg/kg once wkl... View More
Renal Impairment Dose adjustment not necessary
Patients with demyelinating form of Charcot-Marie-Tooth syndrome. Pregnancy and lactation. Intrathecal admin (may be fatal). Patients receiving radiatio... View More
Mode of Action
Vincristine arrests cell division at the metaphase stage by inhibiting microtubule formation in the mitotic spindle.
Elderly. Preexisting pulmonary dysfunction or neuromuscular disease; leucopenia or a complicating infection; impaired liver function; obstructive jaundi... View More
>10% Alopecia (20-70%) Frequency Not Defined Dose limiting neurotoxicity (e.g. motor function impairment, gait abnormalities), hyperuricaemia, bron... View More
Decreased digoxin (tablets) and verapamil absorption with antineoplastic regimens. Increased etoposide serum levels with vincristine. Increased toxicity... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More