Darbesis 6060mcg/.5ml
Injection
Beacon Pharmaceuticals Ltd.
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| Alcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Darbesis 60. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Darbesis 60 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the develo... View More |
| Breastfeeding | SAFE IF PRESCRIBED Darbesis 60 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.... View More |
| Driving | SAFE Darbesis 60 does not usually affect your ability to drive. |
| Kidney | SAFE IF PRESCRIBED Darbesis 60 is safe to use in patients with kidney disease. No dose adjustment of Darbesis 60 is recommended. |
| Liver | CAUTION Darbesis 60 should be used with caution in patients with liver disease. Dose adjustment of Darbesis 60 may be needed. Please consult your doctor. |
Introduction
Darbesis 60 is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. It works by stimulating the bone ma... View More
Uses of Darbesis 60
- Anemia due to chronic kidney disease
- Anemia due to cancer chemotherapy
Side effects of Darbesis 60
- High blood pressure
- Hypersensitivity
How to use Darbesis 60
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Darbesis 60 works
Darbesis 60 is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood... View More
What if you forget to take Darbesis 60?
If you miss a dose of Darbesis 60, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to yo... View More
- Darbesis 60 helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
- It is given as a single injection under your skin.
- Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells and electrolytes such as potassium in your blood.
- Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe... View More
- Stop taking Darbesis 60 and inform your doctor if you develop shortness of breath or skin rash.
Indication
Anaemia of chronic renal failure, Anaemia in chemotherapy patients
Adult Dose
Chronic Kidney Disease-Associated Anemia CKD not on dialysis Recommended starting dose: 0.45 mcg/kg IV/SC q4weeks Consider initiating ESA treatme... View More
Child Dose
Chronic Kidney Disease-Associated Anemia Initiate treatment when the hemoglobin level is <10 g/dL If the hemoglobin level approaches or exceeds 12 g/d... View More
Renal Dose
Chronic Kidney Disease-Associated Anemia CKD not on dialysis Recommended starting dose: 0.45 mcg/kg IV/SC q4weeks Consider initiating ESA treatme... View More
Contraindication
Hypersensitivity, uncontrolled hypertension.
Mode of Action
Darbepoetin alfa is a biosynthetic form of erythropoietin. Recombinant human erythropoietin with sialic acid additions to enhance stability; stimulates ... View More
Precaution
Hypertension; history of seizures; hepatic impairment; sickle cell anaemia; sudden stabing migraine-like pain (warning sign of hypotensive crisis); excl... View More
Side Effect
>10% Cancer patients Fatigue (33%),Diarrhea (22%),Edema (21%),Fever (19%),Dizziness (14%),Arthralgia (13%),Headache (12%),Death (10%) Chronic renal... View More
Pregnancy Category Note
Pregnancy Limited available data on pregnant women are insufficient to determine a drug-associated risk of major birth defects or miscarriage; in anima... View More
Interaction
Antagonism of hypotensive effect and increased risk of hyperkalemia with ACE inhibitors and angiotensin II receptor antagonists. Ethanol.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More