Darbetin 2525mcg/0.42ml
Injection
Healthcare Pharmaceuticals Ltd.
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| Alcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Darbetin 25. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Darbetin 25 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the develo... View More |
| Breastfeeding | SAFE IF PRESCRIBED Darbetin 25 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.... View More |
| Driving | SAFE Darbetin 25 does not usually affect your ability to drive. |
| Kidney | SAFE IF PRESCRIBED Darbetin 25 is safe to use in patients with kidney disease. No dose adjustment of Darbetin 25 is recommended. |
| Liver | CAUTION Darbetin 25 should be used with caution in patients with liver disease. Dose adjustment of Darbetin 25 may be needed. Please consult your doctor. |
Introduction
Darbetin 25 is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. It works by stimulating the bone ma... View More
Uses of Darbetin 25
- Anemia due to chronic kidney disease
- Anemia due to cancer chemotherapy
Side effects of Darbetin 25
- High blood pressure
- Hypersensitivity
How to use Darbetin 25
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Darbetin 25 works
Darbetin 25 is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood... View More
What if you forget to take Darbetin 25?
If you miss a dose of Darbetin 25, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to yo... View More
- Darbetin 25 helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
- It is given as a single injection under your skin.
- Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells and electrolytes such as potassium in your blood.
- Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe... View More
- Stop taking Darbetin 25 and inform your doctor if you develop shortness of breath or skin rash.
Indication
Anaemia of chronic renal failure, Anaemia in chemotherapy patients
Adult Dose
Chronic Kidney Disease-Associated Anemia CKD not on dialysis Recommended starting dose: 0.45 mcg/kg IV/SC q4weeks Consider initiating ESA treatme... View More
Child Dose
Chronic Kidney Disease-Associated Anemia Initiate treatment when the hemoglobin level is <10 g/dL If the hemoglobin level approaches or exceeds 12 g/d... View More
Renal Dose
Chronic Kidney Disease-Associated Anemia CKD not on dialysis Recommended starting dose: 0.45 mcg/kg IV/SC q4weeks Consider initiating ESA treatme... View More
Contraindication
Hypersensitivity, uncontrolled hypertension.
Mode of Action
Darbepoetin alfa is a biosynthetic form of erythropoietin. Recombinant human erythropoietin with sialic acid additions to enhance stability; stimulates ... View More
Precaution
Hypertension; history of seizures; hepatic impairment; sickle cell anaemia; sudden stabing migraine-like pain (warning sign of hypotensive crisis); excl... View More
Side Effect
>10% Cancer patients Fatigue (33%),Diarrhea (22%),Edema (21%),Fever (19%),Dizziness (14%),Arthralgia (13%),Headache (12%),Death (10%) Chronic renal... View More
Pregnancy Category Note
Pregnancy Limited available data on pregnant women are insufficient to determine a drug-associated risk of major birth defects or miscarriage; in anima... View More
Interaction
Antagonism of hypotensive effect and increased risk of hyperkalemia with ACE inhibitors and angiotensin II receptor antagonists. Ethanol.
Alternative brand for Darbetin 25
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More