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Demoxiclave 375250mg+125mg

Tablet
rx_reqRequire Prescription
Drug International Ltd.
Generic: Amoxicillin + Clavulanic Acid (Clavulanate)
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descriptionSafety Advices
AlcoholAlcohol
SAFE
Consuming alcohol with Demoxiclave 375 does not cause any harmful side effects.
PregnancyPregnancy
SAFE IF PRESCRIBED
Demoxiclave 375 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; howeve... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Demoxiclave 375 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and i... View More
DrivingDriving
UNSAFE
Demoxiclave 375 may cause side effects which could affect your ability to drive. Demoxiclave 375 may cause side effects such as allergic reactions, dizz... View More
KidneyKidney
CAUTION
Demoxiclave 375 should be used with caution in patients with kidney disease. Dose adjustment of Demoxiclave 375 may be needed. Please consult your docto... View More
LiverLiver
CAUTION
Demoxiclave 375 should be used with caution in patients with liver disease. Dose adjustment of Demoxiclave 375 may be needed. Please consult your doctor... View More
descriptionMedical Overview

Introduction

Demoxiclave 375 is a penicillin-type of antibiotic that helps your body fight infections caused by bacteria. It is used to treat infections of the lungs... View More

Uses of Demoxiclave 375

  • Bacterial infections

Side effects of Demoxiclave 375

Common
  • Vomiting
  • Nausea
  • Diarrhea

How to use Demoxiclave 375

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Demoxiclave 375 is to be t... View More

How Demoxiclave 375 works

Demoxiclave 375 is a combination of two medicines: Amoxycillin and Clavulanic Acid. Amoxycillin is an antibiotic. It works by preventing the formation o... View More

What if you forget to take Demoxiclave 375?

If you miss a dose of Demoxiclave 375, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back t... View More

quick tipsQuick Tips
  • You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance.
  • Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Diarrhea may occur as a side effect. Taking probiotics along with Demoxiclave 375 may help. Talk to your doctor if you notice bloody stools or develop a... View More
  • Take it with food and plenty of fluids to avoid an upset stomach.
  • Stop taking Demoxiclave 375 and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficu... View More
  • Do not use leftover medicine for treating any infection in the future. Always consult your doctor before taking any antibiotic.
descriptionBrief Description

Indication

Adults: PO: One 375 mg tablet 3 times a day. In severe infection one 625mg tablet 3 times a day or one 1gm tablet two times a day. IV Injection: 1.2 g... View More

Administration

Allopurinol may reduce renal tubular secretion of amoxicillin thus increasing the serum levels of amoxicillin. Concurrent use may reduce the efficacy of... View More

Adult Dose

History of allergy especially to cephalosporins, infectious mononucleosis, severe renal impairment. Lactation: Drug excreted in breast milk; use caut... View More

Renal Dose

Clavulanic acid has a high affinity for and binds to certain ?-lactamases that generally inactivate amoxicillin by hydrolyzing its ?-lactam ring. Combin... View More

Contraindication

Children: 125/31.25-, 250/62.5-mg/5-mL susp: 20–40 mg amoxicillin component/kg/day (max 1,500 mg/day) q8h 200/28.5-, 400/57-mg/5-mL susp: 25-45 mg amox... View More

Mode of Action

Take with meals to avoid GI upset Take suspension at start of meal to enhance absorption Reconstitution: Powd for inj: Dissolve amoxicillin/clavul... View More

Precaution

Bacterial infections, Acute otitis media, Acute bacterial sinusitis, Endocarditis, Dental abscess, Community-acquired pneumonia, Acute uncomplicated UTI... View More

Side Effect

Renal impairment CrCl <30 mL/min: Do not use 875/125 mg tablet or extended-release tablets CrCl 10-30 mL/min: 250-500/125 mg PO q12hr CrCl <10 mL/min... View More

Pregnancy Category Note

>10% Diarrhea (3-34%; varies upon dose and regimen) 1-10% Diaper rash (3.5%),Mycosis (3.3%),Nausea (2-3%),Rash (1-3%),Vomiting (1-2.2%),Loose stool... View More

Interaction

Penicillin allergy.

descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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