Prugen 11mg
Tablet
General Pharmaceuticals Ltd.
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| Alcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Prugen 1. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Information regarding the use of Prugen 1 during pregnancy is not available. Please consult your doctor. |
| Breastfeeding | CONSULT YOUR DOCTOR Prugen 1 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. |
| Driving | UNSAFE Prugen 1 may cause side effects which could affect your ability to drive.
Prugen 1 may cause dizziness and tiredness, especially on the first day of tre... View More |
| Kidney | CAUTION Prugen 1 should be used with caution in patients with severe kidney disease. Dose adjustment of Prugen 1 may be needed. Please consult your doctor. |
| Liver | CAUTION Prugen 1 should be used with caution in patients with severe liver disease. Dose adjustment of Prugen 1 may be needed. Please consult your doctor.
Limit... View More |
Introduction
Prugen 1 is a prescription medicine used in the treatment of constipation. It increases the release of certain chemical that improves the movement of fo... View More
Uses of Prugen 1
- Constipation
Side effects of Prugen 1
- Headache
- Nausea
- Diarrhea
- Abdominal pain
How to use Prugen 1
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prugen 1 may be taken with... View More
How Prugen 1 works
Prugen 1 indirectly stimulates the release of acetylcholine, a chemical messenger that can increase the motility of the intestine.
What if you forget to take Prugen 1?
If you miss a dose of Prugen 1, skip it and continue with your normal schedule. Do not double the dose.
- Prugen 1 helps treat chronic constipation and improve bowel movements, when laxatives have failed to provide adequate relief.
- It can be taken with or without food, at any time of the day.
- It may cause diarrhea. Drink plenty of water and inform your doctor if it bothers you.
- Inform your doctor if your constipation has not improved even after four weeks of taking this medication.
Indication
Chronic idiopathic constipation.
Administration
May be taken with or without food.
Adult Dose
Oral Chronic idiopathic constipation Adult: 2 mg once daily. Elderly: Initially, 1 mg once daily, may increase to 2 mg once daily if necessary. He... View More
Renal Dose
Severe (GFR <30 mL/min/1.73 m2): 1 mg once daily. Patient on dialysis: Contraindicated.
Contraindication
Intestinal obstruction or perforation, obstructive ileus, active severe inflammatory bowel conditions (e.g. Crohn’s disease, toxic megacolon/megarectum,... View More
Mode of Action
Prucalopride is a selective 5-HT4 receptor agonist w/ prokinetic effect. It stimulates peristaltic reflex, intestinal secretions, and GI motility.
Precaution
Patient w/ history of arrhythmias or ischaemic CV disease, severe and unstable concomitant disease (e.g. cancer, AIDS, neurological or psychiatric, pulm... View More
Side Effect
Nervous: Headache, dizziness, fatigue, malaise, tremors. CV: Palpitations. GI: Nausea, abdominal pain and distention, diarrhoea, vomiting, flatulence,... View More
Interaction
May decrease serum concentration of contraceptives (i.e. oestrogens, progestins). May enhance adverse effect of levosulpiride. Increased serum concentra... View More
Alternative brand for Prugen 1
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More