Detomax200mcg/2ml
Injection
Incepta Pharmaceuticals Ltd.
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| Alcohol | UNSAFE Detomax may cause excessive drowsiness with alcohol. |
| Pregnancy | CONSULT YOUR DOCTOR Detomax may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing... View More |
| Breastfeeding | SAFE IF PRESCRIBED Detomax is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. |
| Driving | NOT RELEVANT Not relevant, as Detomax is intended for use in hospitalised patients. |
| Kidney | SAFE IF PRESCRIBED Detomax is safe to use in patients with kidney disease. No dose adjustment of Detomax is recommended. |
| Liver | CAUTION Detomax should be used with caution in patients with liver disease. Dose adjustment of Detomax may be needed. Please consult your doctor. |
Introduction
Detomax is a prescription medicine used to provide sedation (a state of calm, drowsiness, or sleep) for adult patients in intensive care settings. It ma... View More
Uses of Detomax
- Sedative
Side effects of Detomax
- Decreased blood pressure
- Dryness in mouth
How to use Detomax
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Detomax works
Detomax works by modulating the action of certain chemical messengers in the brain that relieves pain and induces sleep.
- Detomax is given as an infusion into the veins by healthcare professionals only.
- Your doctor will closely monitor your heart rate, blood pressure, breathing rate and oxygen level during the treatment.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Indication
ICU Sedation, Fiberoptic Intubation, Procedural Sedation
Administration
IV Preparation Dilute in NS IV Administration Infuse loading dose over 10 min
Adult Dose
ICU Sedation Load: 1 mcg/kg IV over 10 minutes Maintenance 0.2-1.4 mcg/kg/hr IV Titrate less frequently than q30min to prevent hypotension Fibero... View More
Child Dose
Safety and efficacy not established
Renal Dose
Renal Impairment Dose reduction may be required
Contraindication
2nd or 3rd degree AV block (unless paced), uncontrolled hypotension, acute cerebrovascular disorders.
Mode of Action
Centrally acting alpha2-adrenoceptor agonist that has sedative and anesthetic properties possibly by activating G-proteins in the brainstem, which resul... View More
Precaution
Significant CV dysfunction, advanced heart block &/or severe ventricular dysfunction, hypovolemia, DM, chronic HTN. Renal & hepatic impairment. Do not i... View More
Side Effect
>10% Hypotension (28%) 1-10% AFib.Anemia,Bradycardia,Fever,Pleural effusion,Leukocytosis,Pulmonary edema
Pregnancy Category Note
Pregnancy There are no adequate and well-controlled studies of use in pregnant women In an in vitro human placenta study, placental transfer of dexm... View More
Interaction
Enhanced pharmacologic effects of anaesth, sedatives, hypnotics, opiate agonists, other vasodilators or drugs that have negative chronotropic effects (e... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More