Detomax is a prescription medicine used to provide sedation (a state of calm, drowsiness, or sleep) for adult patients in intensive care settings. It ma... View More
Uses of Detomax
Side effects of Detomax
How to use Detomax
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Detomax works
Detomax works by modulating the action of certain chemical messengers in the brain that relieves pain and induces sleep.
ICU Sedation, Fiberoptic Intubation, Procedural Sedation
IV Preparation Dilute in NS IV Administration Infuse loading dose over 10 min
ICU Sedation Load: 1 mcg/kg IV over 10 minutes Maintenance 0.2-1.4 mcg/kg/hr IV Titrate less frequently than q30min to prevent hypotension Fibero... View More
Safety and efficacy not established
Renal Impairment Dose reduction may be required
2nd or 3rd degree AV block (unless paced), uncontrolled hypotension, acute cerebrovascular disorders.
Mode of Action
Centrally acting alpha2-adrenoceptor agonist that has sedative and anesthetic properties possibly by activating G-proteins in the brainstem, which resul... View More
Significant CV dysfunction, advanced heart block &/or severe ventricular dysfunction, hypovolemia, DM, chronic HTN. Renal & hepatic impairment. Do not i... View More
>10% Hypotension (28%) 1-10% AFib.Anemia,Bradycardia,Fever,Pleural effusion,Leukocytosis,Pulmonary edema
Pregnancy Category Note
Pregnancy There are no adequate and well-controlled studies of use in pregnant women In an in vitro human placenta study, placental transfer of dexm... View More
Enhanced pharmacologic effects of anaesth, sedatives, hypnotics, opiate agonists, other vasodilators or drugs that have negative chronotropic effects (e... View More