Detrusin LA is used in the treatment of overactive bladder. It relieves urinary symptoms like frequent urination, urgent need to urinate and inability t... View More
Uses of Detrusin LA
Side effects of Detrusin LA
How to use Detrusin LA
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Detrusin LA may be taken w... View More
How Detrusin LA works
Detrusin LA is an antimuscarinic. It works by relaxing muscles of the urinary bladder and prevents frequent, urgent or uncontrolled urination.
What if you forget to take Detrusin LA?
If you miss a dose of Detrusin LA, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to yo... View More
Oral Overactive Bladder, Urge Incontinence Immediate release: 2 mg PO q12hr. Reduce to 1 mg bid if needed to reduce side effects. Extended release... View More
Child < 18 years: Not recommended
Renal impairment CrCl 10-30 mL/min: Not to exceed 1 mg PO q12hr (immediate release) or 2 mg PO once daily (extended release) CrCl <10 mL/min: Not reco... View More
Severe ulcerative colitis, toxic megacolon, urinary retention, gastric retention, myasthenia gravis, uncontrolled narrow-angle glaucoma, pregnancy.
Mode of Action
Tolterodine is a competitive muscarinic receptor antagonist with actions similar to atropine. It is used in the management of urge urinary incontinence,... View More
Bladder flow obstruction, GI obstructive disorders, renal or hepatic impairment, autonomic neuropathy, hiatus hernia, risk of decreased GI motility, pat... View More
>10% Dry mouth (40%) 1-10% Blurred vision,Constipation,Dizziness,Drowsiness,Dyspepsia,Headache,Xerophthalmia
Increased risk of overdosage with potent CYP3A4 inhibitors e.g. macrolide antibiotics (erythromycin and clarithromycin), azole antifungals (e.g. ketocon... View More