Introduction
Aldactone is a medicine known as a diuretic (water pill). It is mainly used in the treatment of heart failure and high blood pressure. It reduces the sw... View More
Uses of Aldactone
Side effects of Aldactone
How to use Aldactone
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aldactone is to be taken w... View More
How Aldactone works
Aldactone is a potassium-sparing diuretic. It lowers blood pressure and swelling by removing the extra water and electrolytes from the body without loss... View More
What if you forget to take Aldactone?
If you miss a dose of Aldactone, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your... View More
Indication
Oedema, Hirsutism, Hypertension, Hepatic cirrhosis w/ ascites and oedema, Hyperaldosteronism, Severe CHF, Hypokalaemia
Administration
Should be taken with food.
Adult Dose
Oral Oedema Adult: Initially, 100 mg daily, may adjust dose according to response up to 400 mg daily. Hepatic cirrhosis with ascites and oedema Ad... View More
Child Dose
Oral Hepatic cirrhosis with ascites and oedema Child: Initially, 3 mg/kg given in divided doses, may adjust according to response. Diagnosis of pr... View More
Renal Dose
Renal impairment CrCl >50 mL/min/1.73 m²: 12.5-25 mg qDay; use maintenance dose of 25 mg qDay or q12hr after 4 weeks of treatment with potassium <5 mEq... View More
Contraindication
Anuria, hyperkalaemia, acute or progressive renal insufficiency. Addison's disease.
Mode of Action
Spironolactone acts on the distal renal tubules as a competitive antagonist of aldosterone. It increases the excretion of sodium chloride and water whil... View More
Precaution
Patient at risk of developing hyperkalaemia and acidosis, w/ DM. Renal and hepatic impairment. Elderly. Pregnancy and lactation. Patient Counselling Thi... View More
Side Effect
Drowsiness, dizziness, headache, lethargy, leg cramps, GI disturbances (e.g. diarrhoea, cramps), ataxia, mental confusion, rashes, pruritus, alopecia, h... View More
Interaction
Increased risk of hyperkalaemia w/ other K-sparing diuretics or K supplements, ACE inhibitors, angiotensin II receptor antagonists, trilostane, heparin,... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More