Introduction
Dinakion is a medicine used to treat vitamin K deficiency in the body. It helps in improving conditions caused due to low levels of vitamin K in the body. Vitamin K is an important nutrient which is necessary for blood clotting and bone metabolism.
Dinakion is given under the supervision of a healthcare professional and should not be self-administered. You should take it regularly to get the most benefit from it. This medicine may be only part of a complete program of treatment that also includes making changes to your diet and taking vitamin supplements.
Dinakion is generally safe with little or no side effects. However, it may cause pain, redness or swelling at the site of injection in some people.
Before taking this medicine, let your doctor know all other medicines you are taking to make sure you are safe. It is important to ask advise of the doctor before taking any other vitamin supplements.
Side effects of Dinakion
Common
- No common side effects seen
How to use Dinakion
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Dinakion works
Dinakion is a synthetic form of vitamin K. It restores the activity of vitamin K and speeds up the normal blood clotting process to prevent or treat bleeding caused due to too high dose of warfarin.
Indication
Vitamin K deficiency, Over-anticoagulation, Vitamin K deficiency bleeding
Administration
May be taken with or without food.
Adult Dose
Oral
Vitamin K deficiency due to drugs or malabsorption
Adult: 10-40 mg daily.
Over-anticoagulation
Adult: Up to 5 mg may be used. Dose depends on INR and degree of haemorrhage.
Intravenous
Over-anticoagulation
Adult: 0.5-5 mg via slow IV inj. Dose depends on INR and degree of haemorrhage.
Child Dose
Intramuscular
Prophylaxis of vitamin K deficiency bleeding in neonates
Child: Neonate: 0.5-1 mg, given as a single dose via IM inj.
Alternatively, 2 mg may be given orally, followed by a 2nd dose of 2 mg after 4-7 days.
Parenteral
Vitamin K deficiency bleeding in neonates
Child: Infant: 1 mg by IV/IM/SC inj, further doses may be given if necessary
Contraindication
Hypersensitivity.
Mode of Action
Phytomenadione promotes hepatic synthesis of clotting factors. It is a naturally occurring compound that is used to prevent and treat haemorrhages related to vitamin K deficiency.
Precaution
Increased risk of severe haemolytic anaemia in neonates after large doses; severe hepatic impairment; pregnancy. Premature neonates weighing <2.5 kg.
Lactation: Excreted in breast milk; use caution
Side Effect
Anaphylaxis, dyspnoea, cyanosis, pain, swelling, phloebitis at the Inj site, diaphoresis, dizziness, hypotension (rare), allergic reactions after SC and IM inj.
Interaction
Decreased effect of oral anticoagulants.