Drometa4mg/5ml
Injection
Incepta Pharmaceuticals Ltd.
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| Alcohol | CAUTION Caution is advised when consuming alcohol with Drometa. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Drometa is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in s... View More |
| Breastfeeding | CONSULT YOUR DOCTOR Drometa is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. |
| Driving | UNSAFE Drometa may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. |
| Kidney | CONSULT YOUR DOCTOR There is limited information available on the use of Drometa in patients with kidney disease. Please consult your doctor. |
| Liver | CONSULT YOUR DOCTOR There is limited information available on the use of Drometa in patients with liver disease. Please consult your doctor. |
Introduction
Drometa is used to treat or prevent weakening of the bones (osteoporosis) caused by menopause or use of steroids. Using this medicine can reduce your ri... View More
Uses of Drometa
- Osteoporosis
- Hypercalcemia
Side effects of Drometa
- Headache
- Back pain
- Musculoskeletal (bone, muscle or joint) pain
- Heartburn
- Diarrhea
How to use Drometa
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Drometa works
Drometa is a bisphosphonate. It works by suppressing the activity of osteoclasts, cells that cause destruction of bone. This strengthens the bones and m... View More
What if you forget to take Drometa?
If you miss a dose of Drometa. Please consult your doctor.
- You have been prescribed Drometa for the treatment of osteoporosis.
- It may also be used to treat high blood calcium levels (hypercalcemia) or bone damage and pain that may occur with cancer.
- It is given by injection into a vein, usually over at least 15 minutes or as directed by your doctor.
- Drink plenty of fluids to prevent dehydration and kidney damage.
- It can lower the level of calcium in the blood. Take calcium and vitamin D supplements as suggested by your doctor.
- You may develop fever or flu like symptoms, such as chills, tiredness and weakness. These are usually temporary and should go away after a few days. You... View More
- Drometa may cause a rare condition called osteonecrosis of the jaw. Have regular dental check-ups and inform your doctor if you develop sudden pain in y... View More
- Your doctor will monitor your response to Drometa by testing your bone mineral density (BMD). This is usually done every 1-3 years.
- Do not take Drometa if you are pregnant or breastfeeding.
Indication
Hypercalcaemia of malignancy, Bone metastases associated with solid tumours, Multiple myeloma
Adult Dose
Intravenous Hypercalcaemia of malignancy Adult: 4 mg as a single dose by infusion over at least 15 minutes. Retreatment in patients who relapse or who... View More
Child Dose
Safety and efficacy not established
Renal Dose
Renal impairment CrCl >60 mL/min: 4 mg CrCl 50-60 mL/min: 3.5 mg CrCl 40-49 mL/min: 3.3 mg CrCl 30-39 mL/min: 3 mg CrCl <30 mL/min: Not recommende... View More
Contraindication
The drug is contraindicated if patients have hypersensitivity to the active substance or to any of the excipients or to any bisphosphonates, hypocalcaem... View More
Mode of Action
Zoledronic acid, an aminobiphosphonate, is a potent inhibitor of bone resorption. It inhibits osteoclastic activity and skeletal calcium release caused ... View More
Precaution
Patient w/ aspirin-sensitive asthma. Mild to moderate renal impairment. Pregnancy. Patient Counselling This drug may cause dizziness, if affected, do no... View More
Side Effect
Arthralgia, fever, flu-like symptoms, myalgia, headache, pain in extremity, nausea, vomiting, diarrhoea, eye inflammation; alopecia, hyperhidrosis, bone... View More
Interaction
Increased risk of hypocalcaemia with aminoglycosides and loop diuretics. Increased risk renal dysfunction with nephrotoxic agents.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More