Drucil250mg/10ml
Injection
Healthcare Pharmaceuticals Ltd.
Additional Offers
Show all
| Alcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Drucil. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Drucil is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in so... View More |
| Breastfeeding | UNSAFE Drucil is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. |
| Driving | UNSAFE Drucil may cause side effects which could affect your ability to drive.
Drucil can cause side effects such as nausea and can also produce adverse events... View More |
| Kidney | SAFE IF PRESCRIBED Drucil is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Drucil may not be needed in thes... View More |
| Liver | CAUTION Drucil should be used with caution in patients with liver disease. Dose adjustment of Drucil may be needed. Please consult your doctor. |
Introduction
Drucil is used in the treatment of cancers of stomach, colon, rectum, breast, and lungs. It may be used to treat other conditions, as determined by the ... View More
Uses of Drucil
- Cancer
Side effects of Drucil
- Increased risk of infection
- Mouth ulcer
- Vomiting
- Weakness
- Nausea
- Loss of appetite
- Hair loss
- Blisters on fingers/feet
- Decreased blood cells (red cells, white cells, and platelets)
- Diarrhea
How to use Drucil
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Drucil works
Drucil is an anticancer medication. It works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells. This slows the growth... View More
- Drucil helps treat cancers of stomach, colon, rectum, breast, and lungs.
- It is given as an injection into a vein, or as a drip (infusion) into a vein or artery.
- The dose and the number of treatment cycles needed will depend on the type and stage of cancer that is being treated.
- It may cause dizziness and visual changes. Do not drive or do anything requiring concentration until you know how it affects you.
- Your doctor may regularly monitor your blood cells and liver function during treatment with this medicine.
Indication
Palliation of malignant neoplasms, Superficial basal cell carcinoma, Oesophageal carcinoma, Carcinoma of Colon, Carcinoma of Breast, Carcinoma of Ovary,... View More
Administration
IV Preparation IV Push: dose/syringe (concentration: 50 mg/mL); max syringe size for IVP is 30 mL syringe and syringe should be <75% full Continuous... View More
Adult Dose
Adult: IV Palliation of malignant neoplasms 12 mg/kg/day (max: 0.8-1g/day) for 3-4 days, if no toxicity occurs, may be followed after 1 day w/ 6 mg/kg o... View More
Child Dose
Child: Safety & efficacy not established.
Renal Dose
Renal impairment: Dose reduction may be required.
Contraindication
Topical application on mucous membranes, exposure to sunlight, hypersensitivity. Depressed bone marrow function, poor nutritional status, potentially se... View More
Mode of Action
Fluorouracil interferes with DNA synthesis by blocking the conversion of deoxyuridylic acid to thymidylic acid. It also interferes with RNA synthesis. T... View More
Precaution
Regular monitoring of blood counts. History of heart disease, hepatic or renal insufficiency, weak or malnourished patients, patients who with history o... View More
Side Effect
1-10% Loss of appetite,Headache,Nausea,Vomiting,Diarrhea,Mucositis,Myelosuppression,Alopecia,Photosensitivity,Hand-foot syndrome,Maculopapular eruption... View More
Pregnancy Category Note
Pregnancy Category: D Risk Summary There are no adequate and well-controlled studies with fluorouracil in pregnant women. Based on its mechanism of ... View More
Interaction
May increase warfarin effects. May reduce response to vaccines; possibility of generalized infection with live vaccines. Action may be modified by allop... View More
Alternative brand for Drucil
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More