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Healthcare Pharmaceuticals Ltd.
Generic: 5-Fluorouracil (5-FU)
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descriptionSafety Advices
It is not known whether it is safe to consume alcohol with Drucil. Please consult your doctor.
Drucil is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in so... View More
Drucil is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Drucil may cause side effects which could affect your ability to drive. Drucil can cause side effects such as nausea and can also produce adverse events... View More
Drucil is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Drucil may not be needed in thes... View More
Drucil should be used with caution in patients with liver disease. Dose adjustment of Drucil may be needed. Please consult your doctor.
descriptionMedical Overview


Drucil is used in the treatment of cancers of stomach, colon, rectum, breast, and lungs. It may be used to treat other conditions, as determined by the ... View More

Uses of Drucil

  • Cancer

Side effects of Drucil

  • Increased risk of infection
  • Mouth ulcer
  • Vomiting
  • Weakness
  • Nausea
  • Loss of appetite
  • Hair loss
  • Blisters on fingers/feet
  • Decreased blood cells (red cells, white cells, and platelets)
  • Diarrhea

How to use Drucil

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Drucil works

Drucil is an anticancer medication. It works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells. This slows the growth... View More

quick tipsQuick Tips
  • Drucil helps treat cancers of stomach, colon, rectum, breast, and lungs.
  • It is given as an injection into a vein, or as a drip (infusion) into a vein or artery.
  • The dose and the number of treatment cycles needed will depend on the type and stage of cancer that is being treated.
  • It may cause dizziness and visual changes. Do not drive or do anything requiring concentration until you know how it affects you.
  • Your doctor may regularly monitor your blood cells and liver function during treatment with this medicine.
descriptionBrief Description


Palliation of malignant neoplasms, Superficial basal cell carcinoma, Oesophageal carcinoma, Carcinoma of Colon, Carcinoma of Breast, Carcinoma of Ovary,... View More


IV Preparation IV Push: dose/syringe (concentration: 50 mg/mL); max syringe size for IVP is 30 mL syringe and syringe should be <75% full Continuous... View More

Adult Dose

Adult: IV Palliation of malignant neoplasms 12 mg/kg/day (max: 0.8-1g/day) for 3-4 days, if no toxicity occurs, may be followed after 1 day w/ 6 mg/kg o... View More

Child Dose

Child: Safety & efficacy not established.

Renal Dose

Renal impairment: Dose reduction may be required.


Topical application on mucous membranes, exposure to sunlight, hypersensitivity. Depressed bone marrow function, poor nutritional status, potentially se... View More

Mode of Action

Fluorouracil interferes with DNA synthesis by blocking the conversion of deoxyuridylic acid to thymidylic acid. It also interferes with RNA synthesis. T... View More


Regular monitoring of blood counts. History of heart disease, hepatic or renal insufficiency, weak or malnourished patients, patients who with history o... View More

Side Effect

1-10% Loss of appetite,Headache,Nausea,Vomiting,Diarrhea,Mucositis,Myelosuppression,Alopecia,Photosensitivity,Hand-foot syndrome,Maculopapular eruption... View More

Pregnancy Category Note

Pregnancy Category: D Risk Summary There are no adequate and well-controlled studies with fluorouracil in pregnant women. Based on its mechanism of ... View More


May increase warfarin effects. May reduce response to vaccines; possibility of generalized infection with live vaccines. Action may be modified by allop... View More

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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