Efepime IV/IM1gm/vial
Injection
Ziska Pharmaceuticals Ltd.
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| Alcohol | SAFE Consuming alcohol with Efepime IV/IM does not cause any harmful side effects. |
| Pregnancy | SAFE IF PRESCRIBED Efepime IV/IM is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however,... View More |
| Breastfeeding | SAFE IF PRESCRIBED Efepime IV/IM is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is ... View More |
| Driving | CONSULT YOUR DOCTOR It is not known whether Efepime IV/IM alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate a... View More |
| Kidney | CAUTION Efepime IV/IM should be used with caution in patients with kidney disease. Dose adjustment of Efepime IV/IM may be needed. Please consult your doctor. |
| Liver | SAFE IF PRESCRIBED Efepime IV/IM is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Efepime IV/IM may not be n... View More |
Introduction
Efepime IV/IM is an antibiotic that fights bacteria. It is used to treat severe bacterial infections of the skin, lungs, stomach, urinary tract, and blo... View More
Uses of Efepime IV/IM
- Bacterial infections
Side effects of Efepime IV/IM
- Rash
- Itching
- Nausea
- Vomiting
- Headache
- Fever
- Diarrhea
How to use Efepime IV/IM
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Efepime IV/IM works
Efepime IV/IM is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them... View More
What if you forget to take Efepime IV/IM?
If you miss a dose of Efepime IV/IM, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to ... View More
- Your doctor has prescribed Efepime IV/IM to cure your infection and improve your symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder ... View More
- Discontinue Efepime IV/IM and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.... View More
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your sto... View More
- Avoid consuming alcohol while taking Efepime IV/IM as it may cause increased side effects.
Indication
Skin and skin structure infections, Urinary tract infection, Nosocomial pneumonia, Multiple drug resistant pneumonia, Neutropenia
Administration
Reconstitution: IV infusion: Add 5 mL, 10 mL, or 10 mL of a compatible IV soln to a vial labeled as containing 500 mg, 1 g, or 2 g, respectively, to pro... View More
Adult Dose
Adult: IV UTI 0.5-1 g 12 hrly for 7-10 days. Empirical therapy for febrile neutropenia 2 g 8 hrly for 7 days or until resolution of neutropenia. Mod... View More
Child Dose
Child: IV, IM 100 mg/kg/day q12h 150 mg/kg/day empiric therapy of fever with neutropenia q8h 2 mth - 16 yr: >40 kg: 50 mg/kg every 12 hr for 7-10 da... View More
Renal Dose
Renal impairment: Haemodialysis: 1 g on the 1st day of treatment, followed by 0.5 g 24 hrly; dose should be given after haemodialysis on dialysis days... View More
Contraindication
Hypersensitivity to cefepime or other cephalosporins.
Mode of Action
Cefepime is a 4th generation cephalosporin which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall by binding t... View More
Precaution
Renal impairment; history of penicillin or cephalosporin allergy; lactation, pregnancy. Caution when used in patients with history of GI diseases, espec... View More
Side Effect
>10% Positive Coombs test result without hemolysis (16%) 1-10% Rash (1-4%),Elevated alanine aminotransferase (3%),Hypophosphatemia (3%),Diarrhea (<... View More
Pregnancy Category Note
Pregnancy category: B Lactation: Drug enters breast milk; use with caution
Interaction
Increased potential for nephrotoxicity and ototoxicity of aminoglycosides. Increased risk of nephrotoxicity w/ potent diuretics (e.g. furosemide).
Alternative brand for Efepime IV/IM
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More