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Incepta Pharmaceuticals Ltd.
Generic: Letrozole
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descriptionSafety Advices
Consuming alcohol with Endofree does not cause any harmful side effects.
Endofree is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful eff... View More
Endofree is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Endofree may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Endofree is safe to use in patients with kidney disease. No dose adjustment of Endofree is recommended. However, there is limited information on the use... View More
Endofree should be used with caution in patients with liver disease. Dose adjustment of Endofree may be needed. Please consult your doctor.
descriptionMedical Overview


Endofree is used alone or with other treatments, such as surgery or radiation, to treat early breast cancer in postmenopausal women. It can also be used... View More

Uses of Endofree

  • Breast cancer
  • Infertility due to anovulation

Side effects of Endofree

  • Fatigue
  • Hypercholesterolemia (high cholesterol)
  • Increased sweating

How to use Endofree

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Endofree may be taken with... View More

How Endofree works

Endofree is an aromatase inhibitor. It works by decreasing the amount of estrogen (natural female hormone) produced in the body. This decrease in estrog... View More

What if you forget to take Endofree?

If you miss a dose of Endofree, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your ... View More

quick tipsQuick Tips
  • You have been prescribed Endofree for the treatment of breast cancer or infertility due to anovulation.
  • It can be taken with or without food.
  • Do not drive or do anything requiring concentration until you know how Endofree affects you.
  • It may cause increased sweating and hot flushes. Try to keep cool by wearing light and airy clothes.
  • Your doctor may monitor your cholesterol level and bone mineral density (BMD) regularly as Endofree can alter their levels.
  • Do not take Endofree if you are pregnant or breastfeeding
descriptionBrief Description


Breast cancer


May be taken with or without food.

Adult Dose

Oral Advanced or locally advanced breast cancer ; Adjuvant therapy for postmenopausal women with hormone receptor positive early breast cancer Adult: ... View More


Premenopausal women and children; hypersensitivity.

Mode of Action

Letrozole competitively binds to the heme group of aromatase, a cytochrome P450 enzyme which catalyzes conversion of androgen to oestrogen, leading to i... View More


Severe renal impairment; severe hepatic impairment; osteoporosis. Caution when driving or operating machinery. Lactation: not known if excreted in br... View More

Side Effect

Hot flushes, arthralgia, nausea, vomiting, fatigue, dizziness, headache, dyspepsia, constipation, diarrhoea, anorexia, alopoecia, increased sweating, ra... View More


Plasma levels reduced by tamoxifen.

Alternative brand for Endofree
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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