Ezetim is a medicine used to treat high cholesterol. This medicine helps by lowering "bad" cholesterol (LDL) levels in blood. Cholesterol is a fatty sub... View More
Uses of Ezetim
Side effects of Ezetim
How to use Ezetim
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ezetim may be taken with o... View More
How Ezetim works
Ezetim is a cholesterol absorption inhibitors. It reduces the cholesterol absorption from the intestine and lowers the levels of total cholesterol and "... View More
What if you forget to take Ezetim?
If you miss a dose of Ezetim, skip it and continue with your normal schedule. Do not double the dose.
Hyperlipidaemias, Homozygous familial sitosterolaemia, Hypercholesterolaemia
May be taken with or without food.
Oral Hyperlipidaemias; Homozygous familial sitosterolaemia Adult: 10 mg once daily. Hepatic impairment Mild (Child-Pugh class A): Dose adjustment ... View More
Child: >10 yr: 10 mg once daily.
Renal impairment Monotherapy: No dosage adjustment required Moderate to severe: Renal impairment is a risk factor for statin-associated myopathy; caut... View More
Hypersensitivity; moderate to severe liver disease or unexplained serum transaminase elevation. Children <10 yr, lactation.
Mode of Action
Ezetimibe localises at the brush border of the small intestine where it inhibits the absorption of cholesterol, thus decreasing its delivery to the live... View More
Renal or mild hepatic impairment. Monitor LFTs. Immediately discontinue ezetimibe and any HMG-CoA reductase inhibitor or fibrate if myopathy is diagnose... View More
1-10% Diarrhea (4%),Upper respiratory tract symptoms (2-4%),Cough (2-4%),Pain in extremity (3%),Sinusitis (3%),Arthralgia (2-3%),Fatigue (2%),Influenza... View More
Pregnancy Category Note
Pregnancy category: C Lactation: Excretion in milk unknown; use with caution
Reduced absorption w/ colestyramine. Increased plasma concentrations w/ ciclosporin. Concomitant use w/ oral anticoagulants may result in increased INR.... View More