Fosfen is a prescription medicine used for the treatment of epilepsy (seizures). It controls seizures by decreasing the abnormal and excessive activity ... View More
Uses of Fosfen
Side effects of Fosfen
How to use Fosfen
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Fosfen works
Fosfen is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.
What if you forget to take Fosfen?
If you miss a dose of Fosfen, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your re... View More
Fosphenytoin is indicated for short-term parenteral administration when other means of Phenytoin administration are unavailable, inappropriate or deemed... View More
Reconstitution: Prior to IV infusion, dilute Fosphenytoin in 5% Dextrose or 0.9% Saline solution for injection to a concentration ranging from 1.5 to 2... View More
Parenteral Adult: As phenytoin Na equivalents (PSE): (The dose, concentration in dosing solutions, and infusion rate of IV Fosphenytoin is expressed a... View More
Parenteral As phenytoin Na equivalents (PSE): (The dose, concentration in dosing solutions, and infusion rate of IV Fosphenytoin is expressed as Pheny... View More
Renal impairment: Dose reduction or slower infusion may be needed.
Fosphenytoin is contraindicated in patients who have demonstrated hypersensitivity to Fosphenytoin or its ingredients, or to Phenytoin or other Hydantoi... View More
Mode of Action
Fosphenytoin is a diphosphate ester salt of phenytoin which acts as a water soluble prodrug of phenytoin. After admin, plasma esterases convert fospheny... View More
Patient w/ phosphate restriction, hypoalbuminaemia, hypotension, severe myocardial insufficiency, DM. May exacerbate porphyria. Not effective for the tr... View More
>10% IV Pruritis (40-50%),Dizziness (31%),Somnolence (20%),Ataxia (11%) IM Nystagmus (15%) 1-10% IV Tinnitus (6-10%),Deafness (2-5%) IM S... View More
Pregnancy Category Note
Pregnancy In humans, prenatal exposure to phenytoin (the active metabolite of fosphenytoin) may increase risks for congenital malformations and other a... View More
No drugs are known to interfere with the conversion of Fosphenytoin to Phenytoin. Drugs that may increase plasma Phenytoin concentrations include: Acute... View More