Malaria, Nocturnal leg cramps
Intravenous Malaria Adult: As diHCl: Initially, 20 mg/kg to max 1.4 g over 4 hr w/ maintenance infusion started after 8 hr. Maintenance infusions: 1... View More
Intravenous Malaria Child: <5 mg/kg/hr by slow IV infusion.
Renal impairment: Severe: Reduce maintenance dose to 5-7 mg/kg of quinine salt 8 hrly.
Hypersensitivity to quinine, mefloquine or quinidine. Patients w/ nocturnal leg cramps; prolonged QT interval, tinnitus or optic neuritis, myasthenia gr... View More
Mode of Action
Quinine is a cinchona alkaloid and a 4-methanolquinoline. It rapidly acts on blood schizontocide by interfering w/ lysosomal function or nucleic acid sy... View More
Patients w/ cardiac conduction defects, heart block or AF. Pregnancy and lactation. Monitoring Parameters Monitor for signs of cardiotoxicity. Monitor b... View More
<1% Flushing of the skin,Anginal symptoms,Fever,Rash,Pruritus,Hypoglycemia,Epigastric pain,Hemolysis in G6PD deficiency,Thrombocytopenia,Hepatitis,Nigh... View More
Reduced renal clearance of amantadine. Reduced clearance w/ cimetidine. Increased anticoagulant effect of warfarin and other anticoagulants. Reduced pla... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More