Introduction
Abetis Plus 40 is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated it ca... View More
Uses of Abetis Plus 40
Side effects of Abetis Plus 40
How to use Abetis Plus 40
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Abetis Plus 40 may be take... View More
How Abetis Plus 40 works
Abetis Plus 40 is a combination of two medicines: Hydrochlorothiazide and olmesartan which lower blood pressure effectively. Hydrochlorothiazide is a di... View More
Indication
Hypertension, Diabetic nephropathy
Administration
May be taken with or without food.
Adult Dose
Hypertension Initial: 20 mg/12.5 mg PO qDay May increase to 40 mg/25 mg after 2 weeks Hepatic Impairment Dose adjustment not necessary
Child Dose
Safety and efficacy not established
Renal Dose
Renal Impairment CrCl <30 mL/min: Not recommended
Contraindication
Hypersensitivity to olmesartan medoxomil, hydrochlorothiazide or to other sulfonamide-derived drugs. Severe hepatic & renal impairment (CrCl <30 mL/min)... View More
Mode of Action
Hydrochlorothiazide inhibits the reabsorption of Na and chloride in the distal tubules causing increased excretion of Na and water K and hydrogen ions. ... View More
Precaution
Drugs that act on renin-angiotensin system can cause fetal injury and death when used in 2nd and 3rd trimesters of pregnancy. Olmesartan medoxomil shoul... View More
Side Effect
1-10% Olmesartan Dizziness (3%),Headache (1%),Fatigue,Diarrhea (1%),Hyperglycemia (1%),Hypertriglyceridemia (1%),Back pain (1%),Bronchitis (1%),Flu-li... View More
Pregnancy Category Note
Pregnancy Category: C (1st trimester); D (2nd & 3rd trimesters)
Interaction
Olmesartan medoxomil: Increased risk of hypotension, hyperkalemia & changes in renal function w/ aliskiren. May result in deterioration of renal functio... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More