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The ACME Laboratories Ltd.
Generic: Glibenclamide
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descriptionSafety Advices
It is unsafe to consume alcohol with Gluconil.
Gluconil is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, ther... View More
Gluconil is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Mo... View More
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Gluconil is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
Gluconil should be used with caution in patients with liver disease. Dose adjustment of Gluconil may be needed. Please consult your doctor. Use of Gluco... View More
descriptionMedical Overview


Gluconil is a medicine used to treat type 2 diabetes mellitus in adults. It belongs to a group of medicines called sulfonylureas and helps control blood... View More

Uses of Gluconil

  • Type 2 diabetes mellitus

Side effects of Gluconil

  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Headache
  • Dizziness

How to use Gluconil

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gluconil is to be taken wi... View More

How Gluconil works

Gluconil is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.

What if you forget to take Gluconil?

You should skip a dose of Gluconil if a meal is skipped, and add a dose of medicine if you eat an extra meal.

quick tipsQuick Tips
  • Take it shortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals.
  • Be careful while driving or operating machinery until you know how Gluconil affects you.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxie... View More
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing ... View More
descriptionBrief Description


Type 2 DM


Should be taken with food. Take w/ breakfast or the 1st main meal of the day.

Adult Dose

Oral Type 2 diabetes mellitus Adult: Initially, 2.5-5 mg daily, may increase wkly by increments of 2.5-15 mg daily. Doses >10 mg daily should be given... View More

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment: Severe: Contraindicated.


Severe or life-threatening hyperglycaemia, severe liver or renal failure, type 1 diabetes, diabetic ketoacidosis with or without coma, patients with sev... View More

Mode of Action

Glibenclamide lowers blood glucose concentration principally by stimulating secretion of endogenous insulin from the pancreatic beta-cells. Hypoglycaemi... View More


Elderly; malnourished; mild to moderate renal and hepatic disorders. Impaired alertness. Avoid alcohol. Careful monitoring of blood-glucose concentratio... View More

Side Effect

Hypoglycaemia; cholestatic jaundice; agranulocytosis; aplastic anaemia; haemolytic anaemia. Blood dyscrasias (reversible), liver dysfunction, GI symptom... View More


Serum levels may be reduced by colesevelam. May increase hypoglycaemic effect w/ MAOIs, chloramphenicol, fluoroquinolones (e.g. ciprofloxacin), probenec... View More

Alternative brand for Gluconil
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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