Histin used in the treatment of various allergic conditions like runny nose, sneezing, congestion, itching and watery eyes. It also treats nausea, vomit... View More
Uses of Histin
Side effects of Histin
How to use Histin
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Histin may be taken with o... View More
How Histin works
Histin is an antiallergic medication. When your body is exposed to an allergen (pollen, animal dander, house dust etc.), it produces a chemical called h... View More
What if you forget to take Histin?
If you miss a dose of Histin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your re... View More
Allergic conditions, Nausea and vomiting, Motion sickness, Insomnia
May be taken with or without food.
Oral Allergic conditions Adult: As promethazine HCl: 25 mg at night, increase to 25 mg bid if necessary. Alternatively, 10-20 mg 2-3 times daily. P... View More
Oral Allergic conditions Child: As promethazine HCl: 2-5 yr 5-15 mg daily in 1 or 2 divided doses; >5-10 yr 10-25 mg daily in 1 or 2 divided doses... View More
Renal impairment: Dose reduction may be required.
Patients in coma or suffering from CNS depression of any cause. Childn <2 yr. SC and intra-arterial admin. Concurrent use w/ or w/in 14 days of MAOI use... View More
Mode of Action
Promethazine, a phenothiazine derivative, blocks postsynaptic dopaminergic receptors in the brain and has a strong alpha-adrenergic blocking effect. It ... View More
Patient w/ asthma, bronchitis or bronchiectasis; severe coronary artery disease, narrow-angle glaucoma, epilepsy, bladder neck or pyloro-duodenal obstru... View More
Neuroleptic Malignant Syndrome (NMS); CV effects (e.g. bradycardia, tachycardia, transient HTN, hypotension; jaundice, blood dyscrasias, extrapyramidal ... View More
Masks ototoxicity of aminoglycoside antibiotics. May enhance the sedative effects of CNS depressants like alcohol, hypnotics, barbiturates and opioids. ... View More